{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:08:02Z","timestamp":1753862882710,"version":"3.41.2"},"reference-count":2,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Key Clinical Message<\/jats:title><jats:p>Lymphangitic carcinomatosis is a metastatic disease with a poor prognosis and poorly understood pathophysiology. We present a case of rapidly worsening lung adenocarcinoma with diffusely spreading cancerous lymphangitis in lung, mediastinum, retroperitoneum, and gastrointestinal tract. Our findings suggest cancer dissemination in this patient was predominantly caused by direct lymphatic invasion.<\/jats:p>","DOI":"10.1002\/ccr3.9494","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T07:15:39Z","timestamp":1729494939000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Rapidly worsening lung adenocarcinoma due to diffusely spreading lymphangitic carcinomatosis: A case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3257-1639","authenticated-orcid":false,"given":"Satoshi","family":"Tanaka","sequence":"first","affiliation":[{"name":"Respiratory Medicine Toyama City Hospital  Toyama Japan"},{"name":"Respiratory Medicine Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Matsubayashi","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Toyama City Hospital  Toyama Japan"},{"name":"Respiratory Medicine Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunichi","family":"Tamori","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Toyama City Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Saito","sequence":"additional","affiliation":[{"name":"Pathology Toyama City Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nomura","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Toyama City Hospital  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2019.1595982"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.27705"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T05:12:33Z","timestamp":1729746753000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":2,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1002\/ccr3.9494"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9494","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-04-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9494"}}