{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:16:19Z","timestamp":1770268579905,"version":"3.49.0"},"reference-count":39,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n                    <jats:title>Key Clinical Message<\/jats:title>\n                    <jats:p>External muscle stimulation, possibly combined with active muscle contraction, could improve physical functioning and performance in inclusion body myositis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Inclusion body myositis (IBM) is a chronic, progressive inflammatory muscle disease with largely unknown causes. It typically affects men more than women, usually beginning in the latter half of life. IBM leads to muscle weakness and wasting, especially in the arms and legs, which significantly impairs daily functioning and complicates participation in exercise training. Few studies have examined the impact of physical training on fitness, inflammation markers, and quality of life in IBM patients. The patient, a Caucasian male (78.3\u2009kg, 174.0\u2009cm, born October 1948), was diagnosed with IBM in October 2011. From October 2017 to September 2019, he underwent exercise training focused on external muscle stimulation combined with active muscle contractions. Regular assessments included cardiopulmonary exercise testing, functional tests (6\u2010min walking test, modified timed up and go test, modified chair rise test), lung function exams, blood parameters, body composition, and quality of life questionnaires. The decline in physical fitness may have been slowed during the intervention period, as indicated by some improvements like peak oxygen uptake and the functional test results while other parameters remained unchanged or declined like peak power output, fat\u2010free mass or lung functioning. However, a recurrence of his prostate cancer after treatment with androgen deprivation therapy may have led to further declines and thus increased muscle wasting. The data may suggest that supportive exercise programs focusing on external muscle stimulation, possibly combined with active muscle contraction, might improve physical functioning, exercise performance, and quality of life in IBM management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccr3.9539","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T12:07:44Z","timestamp":1730290064000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Whole\u2010body\u2010electro\u2010myostimulation for the care of inclusion body myositis\u2014A case report"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4415-5421","authenticated-orcid":false,"given":"Nils","family":"Freitag","sequence":"first","affiliation":[{"name":"Olympic Training Centre Berlin  Berlin Germany"},{"name":"Department of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine German Sports University  Cologne Germany"},{"name":"Department of Sports Medicine and Exercise Therapy Chemnitz University of Technology  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Dragutinovic","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine German Sports University  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah L.","family":"Notbohm","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine German Sports University  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Filipovic","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine German Sports University  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thorsten","family":"Schiffer","sequence":"additional","affiliation":[{"name":"Outpatient Clinic for Sports Traumatology and Public Health Consultation German Sports University  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilhelm","family":"Bloch","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine German Sports University  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moritz","family":"Schumann","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine and Exercise Therapy Chemnitz University of Technology  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111213252107"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410400407"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneuro0261"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.1020113"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2007.11.001"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.55.2.296"},{"key":"e_1_2_12_8_1","doi-asserted-by":"crossref","unstructured":"DalakasMC.Autoimmune inflammatory myopathies. 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