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The study describes a case involving a patient who initially presented with heart failure symptoms and eventually received a CA diagnosis after 13\u2009months and four primary physician visits, primarily based on discrepancies observed between electrocardiographic and echocardiographic findings, alongside elevated cardiac troponin levels. The case underscores the limited awareness of CA among primary healthcare providers in Ethiopia, contributing to a higher likelihood of misdiagnosis and inappropriate treatment approaches. Additionally, the report discusses the specific challenges associated with diagnosing and managing CA patients. It advocates for essential resources such as heightened clinical suspicion, proficiency in recognizing the characteristic electrocardiogram (ECG) and echocardiographic indicators of CA, and prompt referral to cardiologists.<\/jats:p>","DOI":"10.1002\/ccr3.9582","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:30:26Z","timestamp":1731976226000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Navigating the Diagnostic and Management Challenges of Suspected Cardiac Amyloidosis in Resource\u2010Limited Settings: Ethiopia Experience"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2860-3937","authenticated-orcid":false,"given":"Sura","family":"Markos","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, College of Medicine and Health Sciences Hawassa University  Hawassa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9433-9652","authenticated-orcid":false,"given":"Yegzeru","family":"Belete","sequence":"additional","affiliation":[{"name":"School of Medicine College of Medicine and Health Sciences, Hawassa University  Hawassa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betre","family":"Bikamo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine and Health Sciences Hawassa University  Hawassa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demelash","family":"Ataro","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine and Critical Care, College of Medicine and Health Sciences Hawassa University  Hawassa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.024438"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102017\u2010222852"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11050834"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S414821"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd10060256"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2018.1498782"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57050450"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017256"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12574\u2010015\u20100249\u20101"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-019-1235-x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.038169"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2022.08.009"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2019.09.017"},{"key":"e_1_2_11_15_1","volume-title":"Cardiac Amyloidosis","author":"Shams P.","year":"2023"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.11.022"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/HFJI.HFJI_29_23"},{"issue":"4","key":"e_1_2_11_18_1","first-page":"611","article-title":"Management of Amyloid Cardiomyopathy in Resource\u2010Constrained Settings: Challenges and Opportunities","volume":"3","author":"Singh S.","year":"2021","journal-title":"Cardio Oncology"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131599"},{"key":"e_1_2_11_20_1","first-page":"1052","volume-title":"Braunwald's Heart Disease\u2014A Textbook of Cardiovascular Medicine","author":"Ruberg F. 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