{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T06:25:20Z","timestamp":1775715920040,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Tuberculosis (TB) is an infectious disease caused by <jats:styled-content style=\"fixed-case\"><jats:italic>Mycobacterium tuberculosis<\/jats:italic><\/jats:styled-content> bacteria, which is more prevalent among immunocompromised individuals. According to the distribution of affected organs, this infection can be categorized as either pulmonary or extrapulmonary TB. Immunodeficiency states resulting from rheumatological disorders and the use of immunosuppressive medications, such as in Beh\u00e7et's disease (BD), are potential predisposing factors for TB, particularly in cases involving multiple organs. These situations can introduce challenges in both the diagnosis and treatment of patients. We describe a 43\u2010year\u2010old man with a history of BD who presented with symptoms of weight loss, abdominal pain, and shortness of breath. His chest X\u2010ray revealed cavities and calcifications, while an abdominal X\u2010ray demonstrated signs of intestinal obstruction and adhesions. Subsequent TB diagnosis led to a 6\u2010month course of a TB treatment regimen. Despite treatment initiation, the patient developed a brain abscess 1 year later, necessitating surgical intervention. Following the procedure, he received another 1\u2010year course of a TB treatment regimen and experienced full recovery without any complications during a 2\u2010year follow\u2010up period. Notably, the patient recently received a Sinopharm COVID\u201019 vaccine and subsequently developed seizures that are currently being managed with anticonvulsant therapy. This case report emphasizes the significance of including pulmonary TB in complex medical cases, especially in individuals with autoimmune diseases. Early diagnosis and treatment are crucial for improving outcomes and reducing the risk of complications. Furthermore, it highlights the possible correlation between TB and BD, along with the potential adverse reactions to COVID\u201019 vaccines in this population, which necessitate special consideration by healthcare professionals.<\/jats:p>","DOI":"10.1002\/ccr3.9614","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T06:42:06Z","timestamp":1734072126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Long\u2010Term Journey of a Tuberculosis Patient With Triple Organ Involvement and Rheumatological Disease: A Case Study and Literature Review"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2193-0608","authenticated-orcid":false,"given":"Homina","family":"Saffar","sequence":"first","affiliation":[{"name":"Student Research Committee, Faculty of Medicine Mazandaran University of Medical Sciences  Sari Mazandaran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9419-9238","authenticated-orcid":false,"given":"Pooria","family":"Sobhanian","sequence":"additional","affiliation":[{"name":"Student Research Committee, Faculty of Medicine Mazandaran University of Medical Sciences  Sari Mazandaran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9347-0874","authenticated-orcid":false,"given":"Shahriar","family":"Alian","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, School of Medicine, Antimicrobial Resistance Research Center, Communicable Diseases Institute, Ghaem Shahr Razi Hospital Mazandaran University of Medical Sciences  Sari Mazandaran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9907-8865","authenticated-orcid":false,"given":"David","family":"Darvishnia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Mazandaran University of Medical Sciences  Sari Mazandaran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2653-7685","authenticated-orcid":false,"given":"Mansoureh","family":"Baradaran","sequence":"additional","affiliation":[{"name":"Department of Radiology, Imam Ali Hospital North Khorasan University of Medical Science  Bojnurd North Khorasan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.03.011"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2021.2004864"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1515\/med-2021-0002"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijtb.2020.02.005"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4046\/trd.2015.78.2.47"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2017.10.009"},{"issue":"2","key":"e_1_2_11_8_1","first-page":"001354","article-title":"Beh\u00e7et's Disease and Tuberculosis: A Complex Relationship","volume":"7","author":"Freitas S. 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