{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:08:53Z","timestamp":1753862933102,"version":"3.41.2"},"reference-count":14,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T00:00:00Z","timestamp":1733356800000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Granular cell tumors (GCTs) are uncommon soft tissue neoplasms derived from Schwann cells that can arise from various regions of the body. The majority originate from the head and neck. They are rarely encountered in the gastrointestinal tract and even more rarely in the anorectal region. There is a paucity of literature with only a few case reports of GCT of the anus. We describe a 36\u2010year\u2010old African American male with a long\u2010standing history of human immunodeficiency virus (HIV) infection, multiple perianal abscess and associated fistulas, and an ulcerated perianal lesion that revealed an anal GCT who was treated with excision and surveillance. Given that GCTs in the perianal region are extremely rare, a high index of suspicion of GCT of the anus is critical when patients present with anal masses, ulcers, or abscesses given the extremely poor prognosis of malignant GCTs.<\/jats:p>","DOI":"10.1002\/ccr3.9688","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T04:40:54Z","timestamp":1733460054000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Granular Cell Tumor of the Anus"],"prefix":"10.1002","volume":"12","author":[{"given":"C. H.","family":"Mehta","sequence":"first","affiliation":[{"name":"Department of Surgery Eastern Carolina University Health Medical Center  Greenville North Carolina USA"},{"name":"Brody School of Medicine at East Carolina University  Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. J.","family":"Kantzler","sequence":"additional","affiliation":[{"name":"Department of Surgery Eastern Carolina University Health Medical Center  Greenville North Carolina USA"},{"name":"Brody School of Medicine at East Carolina University  Greenville North Carolina USA"},{"name":"Division of Surgical Oncology, Department of Surgery Eastern Carolina Brody School of Medicine  Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Surgery Eastern Carolina University Health Medical Center  Greenville North Carolina USA"},{"name":"Brody School of Medicine at East Carolina University  Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4574-2094","authenticated-orcid":false,"given":"M. D.","family":"Honaker","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery Eastern Carolina Brody School of Medicine  Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,5]]},"reference":[{"volume-title":"StatPearls","year":"2023","author":"Neelon D.","key":"e_1_2_14_2_1"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjw186"},{"issue":"2","key":"e_1_2_14_4_1","first-page":"161","article-title":"Typical and Atypical Granular Cell Tumors of Soft Tissue: A Clinicopathologic Study of 50 Patients","volume":"148","author":"Stemm M.","year":"2017","journal-title":"American Journal of Pathology"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2015.56.6.1731"},{"issue":"11","key":"e_1_2_14_6_1","first-page":"798","article-title":"Granular Cell Tumors of the Gastrointestinal Tract","volume":"5","author":"Radaelli F.","year":"2009","journal-title":"Gastroenterolog\u00eda y Hepatolog\u00eda"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160909500424"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/usx237"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-015-1877-6"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2010.12.007"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2015136"},{"issue":"1","key":"e_1_2_14_12_1","article-title":"Rare Case of Granular Cell Tumor of Perianal Region: A Case Report and Literature Review","volume":"49","author":"Ma J.","year":"2021","journal-title":"Sage Journals"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.18203\/2349-2902.isj20230670"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-019-04151-x"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000106"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.9688","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T12:20:57Z","timestamp":1748348457000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.9688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/ccr3.9688"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.9688","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-06-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e9688"}}