{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T06:14:41Z","timestamp":1772172881179,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T00:00:00Z","timestamp":1733529600000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Brenner tumors are rare ovarian neoplasms that are typically small and unilateral. Most cases are benign; less than 5% of all Brenner tumors are borderline or proliferative. Brenner tumors originate from the follicular epithelium and consist of ovarian transitional cells surrounded by fibrous tissue. Here we present a case of a 49\u2010year\u2010old premenopausal woman from Northern Tanzania. This patient presented to our facility with acute abdominal pain. She also reported abdominal distention which was first noticed 12\u2009months prior to presentation. Magnetic resonance imaging (MRI) identified a 21\u2009\u00d7\u200917\u2009\u00d7\u20095\u2009cm complex cyst with a thickened wall on the right ovary. The radiological findings were suggestive of an ovarian cystadenoma; multiple intramural and subserosal uterine leiomyomas were also noted. A total abdominal hysterectomy (TAH) and bilateral salpingo\u2010oophorectomy (BSO) was performed. Histopathological findings identified an atypical proliferative borderline Brenner tumor of the right ovary. Postoperative recovery was uneventful, the patient was discharged and managed conservatively postoperatively.<\/jats:p>","DOI":"10.1002\/ccr3.9713","type":"journal-article","created":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T10:00:44Z","timestamp":1733565644000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Management of a Borderline Brenner Tumor of the Ovary in a Premenopausal Woman in Northern Tanzania. A Rare Case Report and Review of the Current Literature"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9221-0452","authenticated-orcid":false,"given":"John","family":"Lugata","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laetitia","family":"Makower","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Rapheal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Centre  Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuph","family":"Mwidibo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4788-8660","authenticated-orcid":false,"given":"Bariki","family":"Mchome","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7226-0168","authenticated-orcid":false,"given":"Alex","family":"Mremi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Kilimanjaro Christian Medical University College  Moshi Tanzania"},{"name":"Department of Pathology Kilimanjaro Christian Medical Centre  Moshi Tanzania"},{"name":"Kilimanjaro Clinical Research Institute  Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,7]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195603\/04)9:2<217::AID-CNCR2820090202>3.0.CO;2-X"},{"key":"e_1_2_13_3_1","first-page":"1098","volume-title":"Robbins and Cotran Pathologic Basis of Disease","author":"Crum C. 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