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One set features a direct trz linkage to the anomeric carbohydrate carbon, while the second set is comprised of an ethyl linker between the two functional units. Deprotection of the carbohydrate afforded hybrid complexes that efficiently catalyse the direct hydrogenation of ketones in water. The catalytic activity of the hybrid complexes was influenced by the pH of the aqueous medium and surpassed the activity of carbohydrate\u2010free or acetyl\u2010protected analogues (&gt;90\u2009% vs 13\u2009% yield). While no enantiomeric induction was observed for the ethyl\u2010linked hybrids, a moderate enantiomeric excess (<jats:italic>ee<\/jats:italic>) was induced by the directly linked systems. Moreover, these carbohydrate\u2010trz hybrid complexes displayed mixed inhibitory activity towards a glycosidase from <jats:italic>H. orenii<\/jats:italic> that contain a glucose binding site.<\/jats:p>","DOI":"10.1002\/cctc.202200086","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T13:45:23Z","timestamp":1645623923000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Carbohydrate\u2010Functionalized Triazolylidene Iridium Complexes: Hydrogenation Catalysis in Water with Asymmetric Induction"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1311-7008","authenticated-orcid":false,"given":"Joseph P.","family":"Byrne","sequence":"first","affiliation":[{"name":"Departement f\u00fcr Chemie Biochemie und Pharmazie Universit\u00e4t Bern  Freiestrasse 3 3012 Bern Switzerland"},{"name":"School of Chemistry National University of Ireland Galway 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