{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:24Z","timestamp":1786977384071,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T00:00:00Z","timestamp":1654473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chronic Diseases and Translational Medicine"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The diagnosis of epilepsy in a child often and understandably causes psychological adjustment difficulties in the parents. To help parents of children with epilepsy cope with stress, it is important to understand how parents cope with the sickness of their child. The objective of this study was to assess factors related to the state of anxiety and depression among parents of children with epilepsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The present study was a cross\u2010sectional study, and the data were collected through an anonymous, Internet\u2010based survey platform between October 2018 and October 2019 from 250 participants aged 22\u201365 years. Participants were invited to fill questionnaires include socioeconomic questionnaire, anxiety, depression, and coping strategies scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>Among the parents of children with epilepsy, 48.8% (122\/250) had depressive symptoms (Patient Health Questionnaire\u20109\u00a0[PHQ\u20109] score\u202f&gt;4) and 46.4% (116\/250) had anxiety symptoms (7\u2010item Generalized Anxiety Disorder [GAD\u20107]\u00a0score\u202f&gt;5). Depression among parents of children with epilepsy was significantly associated with comorbidity (odds ratio [OR]\u2009=\u20090.392, 95% CI\u2009=\u20090.182\u20130.846), a poor parental relationship (OR\u2009=\u20090.283, 95% CI\u2009=\u20090.130\u20130.614), positive coping (OR\u2009=\u20090.947, 95% CI\u2009=\u20090.903\u20130.992), and negative coping (OR\u2009=\u20091.287, 95% CI\u2009=\u20091.179\u20131.405). Anxiety among parents of children with epilepsy was significantly associated with a poor parental relationship (OR\u2009=\u20090.416, 95% CI\u2009=\u20090.207\u20130.835) and negative coping (OR\u2009=\u20091.155, 95% CI\u2009=\u20091.087\u20131.228).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The present study indicates the importance of couple support and providing effective coping to make parents of children with epilepsy more resilient in the presence of negative life events, especially for parents of children with comorbidity with cognitive deficiency.<\/jats:p>\n                  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