{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T17:56:48Z","timestamp":1780595808545,"version":"3.54.1"},"reference-count":353,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cochrane Evidence Synthesis and Methods"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Engaging interest\u2010holders in health care evidence syntheses may make evidence syntheses more relevant, useful, and accessible. However, the best way(s) to engage interest\u2010holders within the evidence synthesis process remain unknown. A previous scoping review collated 291 publications that reported interest\u2010holder engagement in evidence syntheses, but conclusions were limited due to poor reporting. In the present scoping review, our aim was to identify and collate up\u2010to\u2010date publications focussed on interest\u2010holder engagement in healthcare evidence syntheses, describe reported methods of engagement, and compare the results with those from the previous review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We updated a scoping review, following JBI guidance, using a pre\u2010published protocol that defined all key terminology in this field. We systematically searched five electronic databases (MEDLINE, CINAHL, EMBASE, PsycInfo, and SCOPUS). Searches were conducted from January 2016 to February 2024. Records were imported into Covidence and screened by pairs of independent reviewers, including any publications that reported engagement of interest\u2010holders in evidence syntheses. We extracted and coded key data relating to the evidence synthesis topic and ACTIVE framework domains (who was engaged, when, and in what way). Two reviewers independently made a judgment of the comprehensiveness of the description of methods of engagement, using a \u201ctraffic\u2010light\u201d system, coding evidence syntheses with comprehensive descriptions as \u201cgreen,\u201d brief or partial descriptions as \u201camber,\u201d and those with few details as \u201cred\u201d; disagreements were resolved through discussion. Additional detailed data relating to the engagement methods were extracted from \u201cgreen\u201d evidence syntheses. Any disagreements were resolved through discussion. Data were synthesized within tables, and narrative summaries were written to provide an overview of key methods of engaging interest\u2010holders within the identified evidence syntheses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 302 publications published since the previous review. Most (272\/302, 90%) reported interest\u2010holder engagement in a single evidence synthesis; of these, 74% (200\/272) engaged patients and\/or their carers, while 17% (46\/272) engaged other interest\u2010holders only, and the remainder (26\/272, 9.6%) was unclear. Over three\u2010quarters of the evidence syntheses were conducted either in the United Kingdom, United States, Canada, or Australia (215\/272, 79%). Most often (113\/272, 42%), interest\u2010holders were engaged at both the initial (scope and question setting)\n                      <jats:italic>and<\/jats:italic>\n                      final (interpretation of results) review stages (referred to as a \u201ctop and tail\u201d approach). Nineteen percent (51\/272) were judged to provide a comprehensive (\u201cgreen\u201d) description of one or more method(s) or approach(es) to engagement in an evidence synthesis, enabling detailed data extraction and description. Most: engaged patients\/public members and other interest\u2010holder groups (30\/51, 59%); used a \u201cclosed\u201d recruitment strategy (30\/51, 59%); engaged interest\u2010holders during the stage of interpretation of findings (39\/51, 76%); had at least one interest\u2010holder as a co\u2010author (27\/51, 52%). Interest\u2010holders generally attended meetings at which no formal methods of engagement were used. It was common to engage interest\u2010holders in multiple activities throughout the review process.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion\/Conclusion<\/jats:title>\n                    <jats:p>Our international team from the MuSE consortium has updated a previous scoping review, compiling the latest evidence on interest\u2010holder engagement in evidence syntheses. We collated 302 publications and described the methods of interest\u2010holder engagement reported in 51 evidence syntheses that we judged provided the most comprehensive information. Interest\u2010holders have been involved at all stages of the process, using a wide range of engagement approaches, but with no clear patterns linked to the type or focus of evidence syntheses. Most commonly, patients\/public and professional interest\u2010holders were both engaged, but around one\u2010quarter of our examples only engaged patients\/public members, and a small number only engaged professional interest\u2010holders. We identified some distinct engagement strategies and have used these to inform a potential decision tool to support the selection of engagement strategies. We propose recommendations in relation to the conduct and reporting of interest\u2010holder engagement in evidence syntheses and future research to advance this field.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cesm.70066","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T05:49:56Z","timestamp":1768542596000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Methods of Engaging Interest\u2010Holders in Healthcare Evidence Syntheses: A Scoping Review"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4941-7985","authenticated-orcid":false,"given":"Alex","family":"Todhunter\u2010Brown","sequence":"first","affiliation":[{"name":"School of Health &amp; Life Sciences Glasgow Caledonian University Glasgow 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