{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:50:05Z","timestamp":1791600605340,"version":"4.3.4"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":237,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Congenital Anomalies"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Congenital anomalies are a major cause of neonatal morbidity and mortality. In France, nationwide data describing surgical congenital malformations based on standardized hospital databases remain limited. To describe the epidemiology, management, and short\u2010term outcomes of three major surgically relevant congenital malformations\u2014gastroschisis (laparoschisis), omphalocele, and anorectal malformations\u2014using the French national hospital discharge database from 2015 to 2024, and to identify prognostic factors for in\u2010hospital mortality and length of stay. We conducted a retrospective PMSI\u2010based study including neonates with the target malformations identified through ICD\u201010 and CCAM codes. Temporal trends, surgical management, and multivariable determinants of mortality and LOS were examined. National prevalence remained stable across the decade. In\u2010hospital mortality was highest for omphalocele (7.9%), whereas ARMs showed lower mortality but substantial clinical heterogeneity linked to anatomical variability and associated anomalies. Major surgery was independently protective. Higher birthweight and greater gestational age were independently associated with lower in\u2010hospital mortality. From 2015 to 2024, these malformations exhibited stable epidemiology but distinct prognostic profiles in France. Early individualized surgical management and perioperative strategies targeting prematurity and low birthweight may improve outcomes. Nationwide PMSI data support large\u2010scale surveillance but require consideration of coding\u2010related limitations.<\/jats:p>","DOI":"10.1002\/cga.70073","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:38:51Z","timestamp":1787733531000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiology and Prognostic Factors of Three Major Neonatal Congenital Malformations in France: A 10\u2010Year\n                    <scp>PMSI<\/scp>\n                    \u2010Based Retrospective Study (2015\u20132024)"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9506-7934","authenticated-orcid":false,"given":"Xavier Xu","family":"Wang","sequence":"first","affiliation":[{"name":"Health Research and Innovation Delegation (DRSI), Data, Research, Innovation and Medical Information Department (DRIIM) Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coura","family":"Seye","sequence":"additional","affiliation":[{"name":"Health Research and Innovation Delegation (DRSI), Data, Research, Innovation and Medical Information Department (DRIIM) Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Department of Medical Information CHIC  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8486-8939","authenticated-orcid":false,"given":"Camille","family":"Jung","sequence":"additional","affiliation":[{"name":"Health Research and Innovation Delegation (DRSI), Data, Research, Innovation and Medical Information Department (DRIIM) Centre Hospitalier Intercommunal de Cr\u00e9teil (CHIC)  Cr\u00e9teil France"},{"name":"Department of Pediatrics CHIC  Cr\u00e9teil France"},{"name":"University of Paris\u2010Est Cr\u00e9teil  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"543","article-title":"Anomalies cong\u00e9nitales et facteurs \u00e9pid\u00e9miologiques en Tunisie","volume":"102","author":"Nasri K.","year":"2024","journal-title":"La Tunisie M\u00e9dicale"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.5281\/hsd.v21i3.1877"},{"key":"e_1_2_10_4_1","unstructured":"B.Doray \u201cEpid\u00e9miologie clinique g\u00e9n\u00e9tique et pr\u00e9vention des malformations cong\u00e9nitales: Registre des malformations cong\u00e9nitales d'Alsace 1995\u20132009 \u201d2013."},{"key":"e_1_2_10_5_1","volume-title":"Congenital Disorders","author":"WHO"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.16726"},{"key":"e_1_2_10_7_1","unstructured":"INSEE \u201cOne Child out of 250 Dies Before the Age of One in France\u2014Insee Premi\u00e8re\u20142048 \u201dcited December 26 2025 https:\/\/www.insee.fr\/en\/statistiques\/8559246."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.20409"},{"key":"e_1_2_10_9_1","unstructured":"inegalites \u201cEn France les m\u00e8res d\u00e9favoris\u00e9es ont plus de risque de perdre leur b\u00e9b\u00e9 \u201dObservatoire des in\u00e9galit\u00e9s cited December 26 2025 https:\/\/www.inegalites.fr\/mortalite\u2010infantile\u2010france."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.21037\/tp-20-94"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-33"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-90-481-9485-8_20"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2007.00820.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6502a2"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-026297"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116908"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d6749"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.70099"},{"key":"e_1_2_10_19_1","unstructured":"ATIH \u201cPMSI General Information \u201dhttps:\/\/www.atih.sante.fr\/mco\/presentation."},{"key":"e_1_2_10_20_1","unstructured":"Ministere de la Sante \u201cDecret n 94\u2013666 du 27 juillet 1994 relatif aux systemes d'information m\u00e9dicale et a l'analyse de l'activit\u00e9 des \u00e9tablissements de sant\u00e9 publics et priv\u00e9s \u201d(1994) p. 180."},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.664943"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2019.04.003"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/children9101504"},{"key":"e_1_2_10_24_1","volume-title":"International Classification of Diseases 10th Revision (ICD\u201010)","author":"World Health Organization","year":"2010"},{"key":"e_1_2_10_25_1","first-page":"54","article-title":"La r\u00e9volution de la classification commune des actes m\u00e9dicaux: CCAM","volume":"53","author":"Sahraoui F.","year":"2006","journal-title":"ADSP Dossier la R\u00e9forme 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