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In the key step, bromobutenolide <jats:bold>6<\/jats:bold> (obtained from levulinic acid in two steps) was coupled with either of the novel bis(stannanes) <jats:italic>trans<\/jats:italic>,<jats:italic>cis<\/jats:italic>,<jats:italic>trans<\/jats:italic>\u2010<jats:bold>35<\/jats:bold> or <jats:italic>trans<\/jats:italic>,<jats:italic>trans<\/jats:italic>,<jats:italic>trans<\/jats:italic>\u2010<jats:bold>35<\/jats:bold> [each accessible from 3\u2010(tributylstannyl)allyl alcohol (<jats:bold>17<\/jats:bold>) in four steps], giving \u03b3\u2010alkylidenebutenolide <jats:italic>trans<\/jats:italic>,<jats:italic>trans<\/jats:italic>,<jats:italic>trans<\/jats:italic>\u2010<jats:bold>32<\/jats:bold>. This compound was coupled with iododiyne <jats:bold>42<\/jats:bold> or the bromoenediynoate <jats:bold>44<\/jats:bold> leading to dihydroxerulin (<jats:bold>2<\/jats:bold>) and to the (trimethylsilylethyl)ester <jats:bold>45<\/jats:bold> of xerulinic acid, respectively. Deprotection of the latter provided totally synthetic xerulinic acid (<jats:bold>3<\/jats:bold>) for the first time.<\/jats:p>","DOI":"10.1002\/chem.200400913","type":"journal-article","created":{"date-parts":[[2005,1,24]],"date-time":"2005-01-24T11:22:44Z","timestamp":1106565764000},"page":"1610-1624","source":"Crossref","is-referenced-by-count":55,"title":["Stereoselective Syntheses of Dihydroxerulin and Xerulinic Acid, Anti\u2010Hypocholesterolemic Dyes from the Fungus <i>Xerula melanotricha<\/i>"],"prefix":"10.1002","volume":"11","author":[{"given":"Achim","family":"Sorg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Siegel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhard","family":"Br\u00fcckner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,14]]},"reference":[{"key":"e_1_2_5_1_2","unstructured":"\u00a0"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1039\/co9940100287"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(97)00199-3"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/b007590f"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.2174\/1385272013375300"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.43.1413"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3765(19980615)4:6<1116::AID-CHEM1116>3.0.CO;2-5"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-1999-3162"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(99)01030-3"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol990336h"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200453729"},{"key":"e_1_2_5_11_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200453729"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1874-6004(04)80037-6"},{"key":"e_1_2_5_13_2","unstructured":"General references:"},{"key":"e_1_2_5_14_2","volume-title":"Palladium Reagents and Catalysis: Innovations in Organic Synthesis","author":"Tsuji J.","year":"1995"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/9783527612222.ch1"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/9783527612222.ch4"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3757(20001215)112:24<4584::AID-ANGE4584>3.0.CO;2-2"},{"key":"e_1_2_5_17_3","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3773(20001215)39:24<4414::AID-ANIE4414>3.0.CO;2-C"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(00)00438-5"},{"key":"e_1_2_5_19_2","first-page":"27","volume-title":"Grignard Reagents\u2014New Developments","author":"Hill E. 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