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Due to the considerable loading amount of the Co<jats:sup>II<\/jats:sup> complex, another more effective catalyst was pursued by screening (<jats:italic>R<\/jats:italic>,<jats:italic>R<\/jats:italic>)\u2010salen\u2013transition metal complexes. When 10\u2005mol\u2009% of the catalysts were applied with 0.5 equivalent of NCS, a higher level of stereoselectivity was attained with the corresponding Cr<jats:sup>III<\/jats:sup>Cl (84\u2009% <jats:italic>ee<\/jats:italic>), Mn<jats:sup>II<\/jats:sup>Cl (52\u2009% <jats:italic>ee<\/jats:italic>) and Co<jats:sup>II<\/jats:sup> complexes (66\u2009% <jats:italic>ee<\/jats:italic>). Refinement of the conditions established a novel catalytic enantioselective iodocyclization protocol using iodine in the presence of 7\u2005mol\u2009% of (<jats:italic>R<\/jats:italic>,<jats:italic>R<\/jats:italic>)\u2010salen\u2013Cr<jats:sup>III<\/jats:sup>Cl complex activated by 0.7 equivalent of NCS in toluene to induce 74 to 93\u2009% <jats:italic>ee<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/chem.200701199","type":"journal-article","created":{"date-parts":[[2007,10,30]],"date-time":"2007-10-30T13:01:59Z","timestamp":1193749319000},"page":"1023-1028","source":"Crossref","is-referenced-by-count":114,"title":["Asymmetric Iodocyclization Catalyzed by Salen\u2013Cr<sup>III<\/sup>Cl: Its Synthetic Application to Swainsonine"],"prefix":"10.1002","volume":"14","author":[{"given":"Hyo\u2005Young","family":"Kwon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul\u2005Min","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2005Bae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joo\u2010Hack","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2005Ho","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,1,10]]},"reference":[{"key":"e_1_2_6_1_2","unstructured":"\u00a0"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(98)00698-X"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/B978-0-08-052349-1.00098-6","volume-title":"Comprehensive Organic Synthesis, Vol. 4","author":"Harding K. 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