{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:18:11Z","timestamp":1791069491269,"version":"4.1.0"},"reference-count":117,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,2,7]],"date-time":"2014-02-07T00:00:00Z","timestamp":1391731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2014,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reactions of hexaniobate with vanadate in the presence of Ni<jats:sup>2+<\/jats:sup>, Zn<jats:sup>2+<\/jats:sup>, or Cu<jats:sup>2+<\/jats:sup> have furnished three high\u2010nuclear vanadium cluster\u2010substituted heteropolyoxoniobates (HPNs): {Ni(en)<jats:sub>3<\/jats:sub>}<jats:sub>5<\/jats:sub>H{V<jats:sup>V<\/jats:sup>Nb<jats:sub>8<\/jats:sub>V<jats:sup>IV<\/jats:sup><jats:sub>8<\/jats:sub>O<jats:sub>44<\/jats:sub>}<jats:bold>\u22c5<\/jats:bold>9\u2009H<jats:sub>2<\/jats:sub>O (<jats:bold>1<\/jats:bold>), (H<jats:sub>2<\/jats:sub>en)Na<jats:sub>2<\/jats:sub>[{Zn(en)<jats:sub>2<\/jats:sub>(Hen)}{Zn(en)<jats:sub>2<\/jats:sub>(H<jats:sub>2<\/jats:sub>O)}<jats:sub>2<\/jats:sub>{PNb<jats:sub>8<\/jats:sub>V<jats:sup>IV<\/jats:sup><jats:sub>8<\/jats:sub>O<jats:sub>44<\/jats:sub>}]<jats:bold>\u22c5<\/jats:bold>11\u2009H<jats:sub>2<\/jats:sub>O (<jats:bold>2<\/jats:bold>), and Na{Cu(en)<jats:sub>2<\/jats:sub>}<jats:sub>3<\/jats:sub>{[Cu(en)<jats:sub>2<\/jats:sub>]<jats:sub>2<\/jats:sub>[PNb<jats:sub>8<\/jats:sub>V<jats:sup>IV<\/jats:sup><jats:sub>8<\/jats:sub>O<jats:sub>44<\/jats:sub>]}<jats:bold>\u22c5<\/jats:bold>11\u2009H<jats:sub>2<\/jats:sub>O (<jats:bold>3<\/jats:bold>) (en=1,2\u2010diaminoethane). Their structures have been determined and characterized by single\u2010crystal X\u2010ray diffraction analysis, thermogravimetric analysis (TGA), and elemental analysis. Structural analysis has revealed that compounds <jats:bold>1<\/jats:bold>\u2013<jats:bold>3<\/jats:bold> contain similar {V<jats:sub>8<\/jats:sub>}\u2010substituted [X<jats:sup>V<\/jats:sup>Nb<jats:sub>8<\/jats:sub>V<jats:sup>IV<\/jats:sup><jats:sub>8<\/jats:sub>O<jats:sub>44<\/jats:sub>]<jats:sup>11\u2212<\/jats:sup> (X=P, V) clusters, obtained by inserting a {V<jats:sub>8<\/jats:sub>} ring into tetravacant HPN [XNb<jats:sub>8<\/jats:sub>O<jats:sub>36<\/jats:sub>]<jats:sup>27\u2212<\/jats:sup>. To the best of our knowledge, compounds <jats:bold>1<\/jats:bold>\u2013<jats:bold>3<\/jats:bold> represent the first high\u2010nuclear vanadium cluster\u2010substituted HPNs, and compound <jats:bold>1<\/jats:bold> is the largest vanadoniobate cluster yet obtained in HPN chemistry. Nickel and zinc cations have been introduced into HPNs for the first time, which might promise a more diverse set of structures in this family. Antitumor studies have indicated that compounds <jats:bold>1<\/jats:bold> and <jats:bold>2<\/jats:bold> exhibit high activity against human gastric cancer SGC\u20107901 cells, SC\u20101680 cells, and MG\u201063 cells.<\/jats:p>","DOI":"10.1002\/chem.201303995","type":"journal-article","created":{"date-parts":[[2014,2,7]],"date-time":"2014-02-07T06:28:00Z","timestamp":1391754480000},"page":"2840-2848","source":"Crossref","is-referenced-by-count":66,"title":["Unprecedented High\u2010Nuclear Transition\u2010Metal\u2010Cluster\u2010Substituted Heteropolyoxoniobates: Synthesis by {V<sub>8<\/sub>} Ring Insertion into the POM Matrix and Antitumor Activities"],"prefix":"10.1002","volume":"20","author":[{"given":"Jian\u2010Qiang","family":"Shen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2010Ming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang\u2010Guang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"En\u2010Bo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,7]]},"reference":[{"key":"e_1_2_6_1_2","unstructured":"\u00a0"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/355027a0"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr9603946"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr960396q"},{"key":"e_1_2_6_5_2","unstructured":"\u00a0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1083176"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201202750"},{"key":"e_1_2_6_7_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201202750"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr1000578"},{"key":"e_1_2_6_9_2","unstructured":"\u00a0"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs35136f"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs35190k"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs35153f"},{"key":"e_1_2_6_13_2","unstructured":"\u00a0"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs35133a"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1039\/b718374g"},{"key":"e_1_2_6_16_2","unstructured":"\u00a0"},{"key":"e_1_2_6_17_2","first-page":"466","volume":"17","author":"Goiffon A.","year":"1980","journal-title":"Rev. Chim. Miner."},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1039\/c1dt10435g"},{"key":"e_1_2_6_19_2","unstructured":"\u00a0"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic50191a021"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic0601788"},{"key":"e_1_2_6_22_2","unstructured":"\u00a0"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200903970"},{"key":"e_1_2_6_23_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200903970"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja303723u"},{"key":"e_1_2_6_25_2","unstructured":"\u00a0"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1073979"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja201670x"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic048847"},{"key":"e_1_2_6_29_2","unstructured":"\u00a0"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200353410"},{"key":"e_1_2_6_30_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200353410"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/cg0606904"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic061454l"},{"key":"e_1_2_6_33_2","unstructured":"\u00a0"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201104478"},{"key":"e_1_2_6_34_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201104478"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc31284k"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2dt30265a"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201204563"},{"key":"e_1_2_6_38_2","unstructured":"\u00a0"},{"key":"e_1_2_6_39_2","doi-asserted-by":"publisher","DOI":"10.1039\/c1cc12329g"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejic.201201056"},{"key":"e_1_2_6_41_2","unstructured":"\u00a0"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200902483"},{"key":"e_1_2_6_42_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200902483"},{"key":"e_1_2_6_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201100280"},{"key":"e_1_2_6_43_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201100280"},{"key":"e_1_2_6_44_2","doi-asserted-by":"publisher","DOI":"10.1039\/C1CC15520B"},{"key":"e_1_2_6_45_2","unstructured":"\u00a0"},{"key":"e_1_2_6_46_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic202314g"},{"key":"e_1_2_6_47_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cc38981b"},{"key":"e_1_2_6_48_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2ce05333k"},{"key":"e_1_2_6_49_2","unstructured":"\u00a0"},{"key":"e_1_2_6_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0398159"},{"key":"e_1_2_6_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic700845e"},{"key":"e_1_2_6_52_2","unstructured":"\u00a0"},{"key":"e_1_2_6_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200602200"},{"key":"e_1_2_6_53_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200602200"},{"key":"e_1_2_6_54_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic0624118"},{"key":"e_1_2_6_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200700612"},{"key":"e_1_2_6_56_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200801883"},{"key":"e_1_2_6_56_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200801883"},{"key":"e_1_2_6_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-4596(03)00354-2"},{"key":"e_1_2_6_58_2","doi-asserted-by":"publisher","DOI":"10.1039\/b900465c"},{"key":"e_1_2_6_59_2","unstructured":"\u00a0"},{"key":"e_1_2_6_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201103390"},{"key":"e_1_2_6_61_2","doi-asserted-by":"publisher","DOI":"10.1039\/C1CC15684E"},{"key":"e_1_2_6_62_2","unstructured":"\u00a0"},{"key":"e_1_2_6_63_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic50072a029"},{"key":"e_1_2_6_64_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic50072a030"},{"key":"e_1_2_6_65_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2dt31760e"},{"key":"e_1_2_6_66_2","unstructured":"\u00a0"},{"key":"e_1_2_6_67_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic800860q"},{"key":"e_1_2_6_68_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201100004"},{"key":"e_1_2_6_69_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejic.201201117"},{"key":"e_1_2_6_70_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3dt32855d"},{"key":"e_1_2_6_71_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic051155g"},{"key":"e_1_2_6_72_2","unstructured":"\u00a0"},{"key":"e_1_2_6_73_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj3190619"},{"key":"e_1_2_6_74_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00172a014"},{"key":"e_1_2_6_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2009.05.002"},{"key":"e_1_2_6_76_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200500108"},{"key":"e_1_2_6_76_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200500108"},{"key":"e_1_2_6_77_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201007067"},{"key":"e_1_2_6_77_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201007067"},{"key":"e_1_2_6_78_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic301892s"},{"key":"e_1_2_6_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2006.02.004"},{"key":"e_1_2_6_80_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/42.2.199"},{"key":"e_1_2_6_81_2","first-page":"319","volume":"18","author":"Jasmin C.","year":"1973","journal-title":"Biomedicine"},{"key":"e_1_2_6_82_2","unstructured":"\u00a0"},{"key":"e_1_2_6_83_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201001626"},{"key":"e_1_2_6_84_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic3010079"},{"key":"e_1_2_6_85_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2dt31784b"},{"key":"e_1_2_6_86_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cc41628c"},{"key":"e_1_2_6_87_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic400019r"},{"key":"e_1_2_6_88_2","unstructured":"\u00a0"},{"key":"e_1_2_6_89_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja001809e"},{"key":"e_1_2_6_90_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00032a016"},{"key":"e_1_2_6_91_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201000824"},{"key":"e_1_2_6_92_2","unstructured":"\u00a0"},{"key":"e_1_2_6_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2008.05.015"},{"key":"e_1_2_6_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-1693(02)00991-X"},{"key":"e_1_2_6_95_2","doi-asserted-by":"publisher","DOI":"10.1021\/cg1014829"},{"key":"e_1_2_6_96_2","doi-asserted-by":"publisher","DOI":"10.1039\/a900928k"},{"key":"e_1_2_6_97_2","doi-asserted-by":"publisher","DOI":"10.1039\/b202540j"},{"key":"e_1_2_6_98_2","doi-asserted-by":"publisher","DOI":"10.1039\/b010227j"},{"key":"e_1_2_6_99_2","unstructured":"\u00a0"},{"key":"e_1_2_6_100_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3757(19990712)111:13\/14<2063::AID-ANGE2063>3.0.CO;2-8"},{"key":"e_1_2_6_100_3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3773(19990712)38:13\/14<1937::AID-ANIE1937>3.0.CO;2-5"},{"key":"e_1_2_6_101_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201002563"},{"key":"e_1_2_6_101_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201002563"},{"key":"e_1_2_6_102_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201200261"},{"key":"e_1_2_6_103_2","unstructured":"\u00a0"},{"key":"e_1_2_6_104_2","unstructured":"G.\u2005M. Sheldrick SHELXL\u201097 Program for Crystal Structure Refinement University of G\u00f6ttingen G\u00f6ttingen Germany 1997;"},{"key":"e_1_2_6_105_2","unstructured":"G.\u2005M. Sheldrick SHELXS\u201097 Program for Crystal Structure Solution University of G\u00f6ttingen G\u00f6ttingen Germany 1997."}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fchem.201303995","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.201303995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:44:46Z","timestamp":1760298286000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.201303995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,7]]},"references-count":117,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,3,3]]}},"alternative-id":["10.1002\/chem.201303995"],"URL":"https:\/\/doi.org\/10.1002\/chem.201303995","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,7]]}}}