{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:28:05Z","timestamp":1769164085869,"version":"3.49.0"},"reference-count":101,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T00:00:00Z","timestamp":1515024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21472058, 21472057, 21622201 and 21232003"],"award-info":[{"award-number":["21472058, 21472057, 21622201 and 21232003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In contrast to the plethora of catalytic systems that enable access to any enantiomers of the chiral products by simply choosing between a pair of enantiomeric or pseudoenantiomeric chiral catalysts, few analogously effective protocols exist for the synthesis of compounds bearing multiple stereogenic centers with full control of the absolute and relative stereochemical configurations. Here, we report the application of our previously developed modular phosphoramidite\u2010thioether ligands for the copper\u2010catalyzed diastereodivergent asymmetric 1,3\u2010dipolar cycloaddition of azomethine ylides and nitroalkenes. Our catalytic system enables wide substrate scope, great stereochemical control, and high reaction efficiency.<\/jats:p>","DOI":"10.1002\/chem.201705301","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T10:06:38Z","timestamp":1512554798000},"page":"1714-1719","source":"Crossref","is-referenced-by-count":36,"title":["A Highly Enantioselective Copper\/Phosphoramidite\u2010Thioether\u2010Catalyzed Diastereodivergent 1,3\u2010Dipolar Cycloaddition of Azomethine Ylides and Nitroalkenes"],"prefix":"10.1002","volume":"24","author":[{"given":"Bin","family":"Feng","sequence":"first","affiliation":[{"name":"CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry Central China Normal University  152 Luoyu Road, Wuhan Hubei 430079 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010Rong","family":"Chen","sequence":"additional","affiliation":[{"name":"CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry Central China Normal University  152 Luoyu Road, Wuhan Hubei 430079 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun\u2010Fang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry University of California  Los Angeles California 90095 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Lu","sequence":"additional","affiliation":[{"name":"CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry Central China Normal University  152 Luoyu Road, Wuhan Hubei 430079 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9318-6021","authenticated-orcid":false,"given":"Wen\u2010Jing","family":"Xiao","sequence":"additional","affiliation":[{"name":"CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry Central China Normal University  152 Luoyu Road, Wuhan Hubei 430079 P. R. China"},{"name":"State Key Laboratory of Applied Organic Chemistry Lanzhou University  Lanzhou 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,4]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd915"},{"key":"e_1_2_2_3_1","unstructured":"\u00a0"},{"key":"e_1_2_2_4_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2490(96)80003-7","volume":"28","author":"Gross A. 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Drug Res."},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/9781420092394"},{"key":"e_1_2_2_6_2","volume-title":"Foye's Principles of Medicinal Chemistry","year":"2013"},{"key":"e_1_2_2_7_1","unstructured":"\u00a0"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-58571-5"},{"key":"e_1_2_2_9_2","volume-title":"Asymmetric Catalysis: New Concepts and Methods","year":"2008"},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/9780470584248"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-095167-6.00502-4"},{"key":"e_1_2_2_12_1","volume-title":"Classics in Stereoselective Synthesi","year":"2009"},{"key":"e_1_2_2_13_1","unstructured":"For comprehensive reviews 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These data are provided free of charge byThe Cambridge Crystallographic Data Centre."},{"key":"e_1_2_2_86_1","unstructured":"Please see the Supporting Information for more details."}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fchem.201705301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.201705301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T15:00:55Z","timestamp":1760281255000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.201705301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,4]]},"references-count":101,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1002\/chem.201705301"],"URL":"https:\/\/doi.org\/10.1002\/chem.201705301","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,4]]}}}