{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T15:12:38Z","timestamp":1776784358041,"version":"3.51.2"},"reference-count":50,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T00:00:00Z","timestamp":1520899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["1508085MB26"],"award-info":[{"award-number":["1508085MB26"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2018,4,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A sodium chloride crystal\u2010driven spontaneous \u2032hot spot\u2032 structure was demonstrated as a SERS\u2010active platform, to get reproducible SERS signals, and eliminate the need for mapping large areas, in comparison with solution phase testing. During the process of solvent evaporation, the crystals produced induced silver aggregates to assemble around themselves. The micro\u2010scale crystals can also act as a template to obtain an optical position, such that the assembled hot area is conveniently located during SERS measurements. More importantly, the chloride ions added in colloids can also replace the citrate and on the surface of the silver sol, and further decrease the background interference. High quality SERS spectra from heroin, methamphetamine (MAMP), and cocaine have been obtained on the crystal\u2010driven hot spot structure with high sensitivity and credible reproducibility. This approach can not only bring the nanoparticles to form plasmonic hot spots in a controlled way, and thus provide high sensitivity, but also potentially be explored as an active substrate for label\u2010free detection of other illicit drugs or additives.<\/jats:p>","DOI":"10.1002\/chem.201800487","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T22:06:46Z","timestamp":1519682806000},"page":"4800-4804","source":"Crossref","is-referenced-by-count":27,"title":["Sodium Chloride Crystal\u2010Induced SERS Platform for Controlled Highly Sensitive Detection of Illicit Drugs"],"prefix":"10.1002","volume":"24","author":[{"given":"Borong","family":"Yu","sequence":"first","affiliation":[{"name":"Institute of Intelligent Machines Institution Chinese Academy of Sciences  Hefei 230031 P. R. China"},{"name":"Department of Materials Science and Engineering University of Science and Technology of China  Hefei 230026 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pan","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Machines Institution Chinese Academy of Sciences  Hefei 230031 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binbin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Machines Institution Chinese Academy of Sciences  Hefei 230031 P. R. China"},{"name":"Department of Materials Science and Engineering University of Science and Technology of China  Hefei 230026 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianghu","family":"Tang","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Machines Institution Chinese Academy of Sciences  Hefei 230031 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaofei","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Machines Institution Chinese Academy of Sciences  Hefei 230031 P. R. China"},{"name":"Department of Materials Science and Engineering University of Science and Technology of China  Hefei 230026 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6559-6947","authenticated-orcid":false,"given":"Liangbao","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Machines Institution Chinese Academy of Sciences  Hefei 230031 P. R. China"},{"name":"Department of Materials Science and Engineering University of Science and Technology of China  Hefei 230026 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,13]]},"reference":[{"key":"e_1_2_2_1_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00172J"},{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b04011"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2015.08.012"},{"key":"e_1_2_2_4_1","unstructured":"\u00a0"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1039\/a827241z"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.83.4357"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.2812122"},{"key":"e_1_2_2_8_1","unstructured":"\u00a0"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201303384"},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR00944H"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00195E"},{"key":"e_1_2_2_12_1","unstructured":"\u00a0"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl903693v"},{"key":"e_1_2_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature11653"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl304078v"},{"key":"e_1_2_2_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja2088713"},{"key":"e_1_2_2_17_1","unstructured":"\u00a0"},{"key":"e_1_2_2_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201201690"},{"key":"e_1_2_2_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/la802319c"},{"key":"e_1_2_2_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat1211"},{"key":"e_1_2_2_21_1","unstructured":"\u00a0"},{"key":"e_1_2_2_22_2","doi-asserted-by":"publisher","DOI":"10.1039\/C2LC20926H"},{"key":"e_1_2_2_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201100641"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00265"},{"key":"e_1_2_2_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/j100214a025"},{"key":"e_1_2_2_26_1","unstructured":"\u00a0"},{"key":"e_1_2_2_27_2","doi-asserted-by":"publisher","DOI":"10.1006\/jcis.1995.1467"},{"key":"e_1_2_2_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4555(199808)29:8<681::AID-JRS287>3.0.CO;2-J"},{"key":"e_1_2_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2006.08.054"},{"key":"e_1_2_2_30_1","volume-title":"Principles of Surface-Enhanced Raman Spectroscopy","author":"La Ru E. C.","year":"2009"},{"key":"e_1_2_2_31_1","unstructured":"\u00a0"},{"key":"e_1_2_2_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp055866b"},{"key":"e_1_2_2_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac403974n"},{"key":"e_1_2_2_34_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b01426"},{"key":"e_1_2_2_35_1","unstructured":"\u00a0"},{"key":"e_1_2_2_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2010.01562.x"},{"key":"e_1_2_2_37_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3an00673e"},{"key":"e_1_2_2_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/la00010a021"},{"key":"e_1_2_2_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp052184f"},{"key":"e_1_2_2_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/es104205a"},{"key":"e_1_2_2_41_1","unstructured":"\u00a0"},{"key":"e_1_2_2_42_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf801969v"},{"key":"e_1_2_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2013.09.088"},{"key":"e_1_2_2_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/es051043o"},{"key":"e_1_2_2_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl034676e"},{"key":"e_1_2_2_46_1","unstructured":"\u00a0"},{"key":"e_1_2_2_47_2","doi-asserted-by":"publisher","DOI":"10.1366\/0003702001949014"},{"key":"e_1_2_2_48_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b00137"},{"key":"e_1_2_2_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2016.10.101"},{"key":"e_1_2_2_50_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC05979E"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fchem.201800487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.201800487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:13:59Z","timestamp":1760296439000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.201800487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,13]]},"references-count":50,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2018,4,3]]}},"alternative-id":["10.1002\/chem.201800487"],"URL":"https:\/\/doi.org\/10.1002\/chem.201800487","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,13]]}}}