{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:45:02Z","timestamp":1787165102015,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"58","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001736","name":"German-Israeli Foundation for Scientific Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001736","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2019,10,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A calix[4]arene ligand, in which two of the phenol functions are replaced by pyrazole units has been employed to mimic the His\n                    <jats:sub>2<\/jats:sub>\n                    \u2013Tyr\n                    <jats:sub>2<\/jats:sub>\n                    (His: histidine, Tyr: tyrosine) ligand sphere within the active site of the galactose oxidase (GO). The calixarene backbone forces the corresponding copper(II) complex into a see\u2010saw\u2010type structure, which is hitherto unprecedented in GO modelling chemistry. It undergoes a one\u2010electron oxidation that is centered at the phenolate donor leading to a copper\u2010coordinated phenoxyl radical like in the GO. Accordingly, the complex was tested as a functional model and indeed proved capable of oxidizing benzyl alcohol to the respective aldehyde using two phenoxyl\u2010radical equivalents as oxidants. Finally, the results show that the calixarene platform can be utilized to arrange donor functions to biomimetic binding pockets that allow for the creation of novel types of model compounds.\n                  <\/jats:p>","DOI":"10.1002\/chem.201903820","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T08:34:51Z","timestamp":1566549291000},"page":"13285-13289","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Oxygen\u2010Depleted Calixarenes as Ligands for Molecular Models of Galactose Oxidase"],"prefix":"10.1002","volume":"25","author":[{"given":"Matthias","family":"Keck","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Chemie Humboldt-Universit\u00e4t zu Berlin  Brook-Taylor-Strasse 2 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santina","family":"Hoof","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie Humboldt-Universit\u00e4t zu Berlin  Brook-Taylor-Strasse 2 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Herwig","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie Humboldt-Universit\u00e4t zu Berlin  Brook-Taylor-Strasse 2 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadi","family":"Vigalok","sequence":"additional","affiliation":[{"name":"School of Chemistry Tel Aviv University  1 Ramat Aviv 69978 Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0751-1386","authenticated-orcid":false,"given":"Christian","family":"Limberg","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie Humboldt-Universit\u00e4t zu Berlin  Brook-Taylor-Strasse 2 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,19]]},"reference":[{"key":"e_1_2_2_1_1","volume-title":"Calixarenes","author":"Gutsche C. 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