{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T17:59:53Z","timestamp":1783619993499,"version":"3.55.0"},"reference-count":101,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T00:00:00Z","timestamp":1576800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["2184115"],"award-info":[{"award-number":["2184115"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21702013"],"award-info":[{"award-number":["21702013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2020,1,16]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Herein, we report a highly efficient ZnI<jats:sub>2<\/jats:sub>\u2010triggered oxidative cross\u2010coupling reaction of P(O)\u2212H compounds and amines. This operationally simple protocol provides unprecedented generic access to phosphinic amides\/phosphoramidate derivatives in good yields and short reaction time. Besides, the reaction proceeds under mild conditions, which avoids the use of hazardous reagents, and is applicable to scale\u2010up syntheses as well as late\u2010stage functionalization of drug molecules. The stereospecific coupling is also achieved from readily available optically enriched P(O)\u2212H compounds.<\/jats:p>","DOI":"10.1002\/chem.201904237","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T07:35:22Z","timestamp":1571384122000},"page":"881-887","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Practical Synthesis of Phosphinic Amides\/Phosphoramidates through Catalytic Oxidative Coupling of Amines and P(O)\u2212H Compounds"],"prefix":"10.1002","volume":"26","author":[{"given":"Chen","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Organic Chemistry Beijing Advanced Innovation Center for, Soft Matter Science and Engineering College of Science Beijing University of Chemical Technology  Beijing 100029 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry Beijing Advanced Innovation Center for, Soft Matter Science and Engineering College of Science Beijing University of Chemical Technology  Beijing 100029 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanxin","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry Beijing Advanced Innovation Center for, Soft Matter Science and Engineering College of Science Beijing University of Chemical Technology  Beijing 100029 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry Beijing Advanced Innovation Center for, Soft Matter Science and Engineering College of Science Beijing University of Chemical Technology  Beijing 100029 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry Beijing Advanced Innovation Center for, Soft Matter Science and Engineering College of Science Beijing University of Chemical Technology  Beijing 100029 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Wang","sequence":"additional","affiliation":[{"name":"Hefei National Laboratory for Physical Sciences at Microscale CAS Key Laboratory of Soft Matter Chemistry &amp; Center for Excellence in Molecular Synthesis of, the Chinese Academy of Sciences University of Science and Technology of China Institution  Hefei 230026 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3825-9344","authenticated-orcid":false,"given":"Jiajing","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry Beijing Advanced Innovation Center for, Soft Matter Science and Engineering College of Science Beijing University of Chemical Technology  Beijing 100029 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,20]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"\u00a0"},{"key":"e_1_2_7_2_2","first-page":"5","volume-title":"Handbook of Organophosphorus Chemistry","year":"1992"},{"key":"e_1_2_7_3_2","volume-title":"A Guide to Organophosphorus Chemistry","author":"Quin L. D.","year":"2000"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol702074a"},{"key":"e_1_2_7_5_1","unstructured":"\u00a0"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6700(02)00018-7"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.7b01915"},{"key":"e_1_2_7_8_1","unstructured":"\u00a0"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b00734"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b00469"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(09)60968-5"},{"key":"e_1_2_7_12_2","unstructured":"J.-P.Sommadossi G.Gosselin C.Pierra C.Perigaud S.Peyrottes US 7902202B2 2011."},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2174\/1385272819666140829011741"},{"key":"e_1_2_7_14_1","unstructured":"\u00a0"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.07.057"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol026618q"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo034331g"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol051104n"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2004.01.003"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.200900279"},{"key":"e_1_2_7_21_1","unstructured":"\u00a0"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1039\/p19850000461"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.200300396"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.08.122"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja512029x"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA05264A"},{"key":"e_1_2_7_27_1","unstructured":"\u00a0"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.10.117"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1039\/jr9450000660"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b03056"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b02073"},{"key":"e_1_2_7_32_1","unstructured":"\u00a0"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8GC00482J"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwu076"},{"key":"e_1_2_7_35_1","unstructured":"\u00a0"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1039\/9781782620082"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar800164n"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201304268"},{"key":"e_1_2_7_38_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201304268"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs15323h"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cs60082c"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr100280d"},{"key":"e_1_2_7_42_1","unstructured":"\u00a0"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC01277A"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC02730F"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6CC03709G"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7GC01989K"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7RA00352H"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB02826E"},{"key":"e_1_2_7_49_1","unstructured":"\u00a0"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cs60464k"},{"key":"e_1_2_7_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2017.10.001"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00397"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00475"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00271"},{"key":"e_1_2_7_55_1","unstructured":"\u00a0"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2014.09.021"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2013.09.006"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.01.064"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2016.05.076"},{"key":"e_1_2_7_60_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.6b01210"},{"key":"e_1_2_7_61_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cc45680c"},{"key":"e_1_2_7_62_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201501068"},{"key":"e_1_2_7_63_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol402956b"},{"key":"e_1_2_7_64_2","volume-title":"Recent Advances in H-Phosphonate Chemistry. Part 1. H-Phosphonate Esters: Synthesis and Basic Reactions","author":"Sobkowski M.","year":"2015"},{"key":"e_1_2_7_65_2","doi-asserted-by":"publisher","DOI":"10.1007\/s41061-018-0200-9"},{"key":"e_1_2_7_66_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b04081"},{"key":"e_1_2_7_67_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo100473s"},{"key":"e_1_2_7_68_1","unstructured":"\u00a0"},{"key":"e_1_2_7_69_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA23096A"},{"key":"e_1_2_7_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2018.05.028"},{"key":"e_1_2_7_71_1","unstructured":"For selected recent reports see:"},{"key":"e_1_2_7_72_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.5b02161"},{"key":"e_1_2_7_73_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b00277"},{"key":"e_1_2_7_74_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b01360"},{"key":"e_1_2_7_75_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b01412"},{"key":"e_1_2_7_76_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b01684"},{"key":"e_1_2_7_77_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b03392"},{"key":"e_1_2_7_78_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00398"},{"key":"e_1_2_7_79_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo502933e"},{"key":"e_1_2_7_80_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b01933"},{"key":"e_1_2_7_81_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol5027393"},{"key":"e_1_2_7_82_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol402987u"},{"key":"e_1_2_7_83_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol502431b"},{"key":"e_1_2_7_84_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol4023936"},{"key":"e_1_2_7_85_2","doi-asserted-by":"publisher","DOI":"10.1039\/c1cc12885j"},{"key":"e_1_2_7_86_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol1023085"},{"key":"e_1_2_7_87_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b03171"},{"key":"e_1_2_7_88_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b01516"},{"key":"e_1_2_7_89_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201500619"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201100100"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo501326r"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1021\/ed1003806"},{"key":"e_1_2_7_93_1","unstructured":"For details see the Supporting Information."},{"key":"e_1_2_7_94_1","unstructured":"\u00a0"},{"key":"e_1_2_7_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2012.09.056"},{"key":"e_1_2_7_96_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo101540d"},{"key":"e_1_2_7_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2013.09.001"},{"key":"e_1_2_7_98_1","unstructured":"\u00a0"},{"key":"e_1_2_7_99_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6CC00370B"},{"key":"e_1_2_7_100_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b00464"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fchem.201904237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.201904237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/chem.201904237","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.201904237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T09:08:23Z","timestamp":1760260103000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.201904237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,20]]},"references-count":101,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,1,16]]}},"alternative-id":["10.1002\/chem.201904237"],"URL":"https:\/\/doi.org\/10.1002\/chem.201904237","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,20]]},"assertion":[{"value":"2019-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}