{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:31:52Z","timestamp":1790685112265,"version":"4.1.0"},"reference-count":75,"publisher":"Wiley","issue":"58","license":[{"start":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T00:00:00Z","timestamp":1599782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004955","name":"\u00d6sterreichische Forschungsf\u00f6rderungsgesellschaft","doi-asserted-by":"publisher","award":["862766"],"award-info":[{"award-number":["862766"]}],"id":[{"id":"10.13039\/501100004955","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2020,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The use of gases as reagents in organic synthesis can be very challenging, particularly at a laboratory scale. This Concept takes into account recent studies to make the case that gases can indeed be efficiently and safely formed from relatively inexpensive commercially available reagents for use in a wide range of organic transformations. In particular, we argue that the exploitation of continuous flow membrane reactors enables the effective separation of the chemistry necessary for gas formation from the chemistry for gas consumption, with these two stages often containing incompatible chemistry. The approach outlined eliminates the need to store and transport excessive amounts of potentially toxic, reactive or explosive gases. The on\u2010demand generation, separation and reaction of a number of gases, including carbon monoxide, diazomethane, trifluoromethyl diazomethane, hydrogen cyanide, ammonia and formaldehyde, is discussed.<\/jats:p>","DOI":"10.1002\/chem.202001942","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T11:12:15Z","timestamp":1591701135000},"page":"13108-13117","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Membrane Microreactors for the On\u2010Demand Generation, Separation, and Reaction of Gases"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5939-920X","authenticated-orcid":false,"given":"Christopher A.","family":"Hone","sequence":"first","affiliation":[{"name":"Center for Continuous Flow Synthesis and Processing (CCFLOW) Research Center Pharmaceutical Engineering GmbH (RCPE)  Inffeldgasse 13 8010 Graz Austria"},{"name":"Institute of Chemistry University of Graz, NAWI Graz  Heinrichstrasse 28 8010 Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2983-6007","authenticated-orcid":false,"given":"C. Oliver","family":"Kappe","sequence":"additional","affiliation":[{"name":"Center for Continuous Flow Synthesis and Processing (CCFLOW) Research Center Pharmaceutical Engineering GmbH (RCPE)  Inffeldgasse 13 8010 Graz Austria"},{"name":"Institute of Chemistry University of Graz, NAWI Graz  Heinrichstrasse 28 8010 Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,11]]},"reference":[{"key":"e_1_2_9_1_1","first-page":"475","volume":"55","author":"Lian Y. Q.","year":"2016","journal-title":"Mech. Chem. Eng. Trans."},{"issue":"4","key":"e_1_2_9_2_1","first-page":"51","volume":"30","author":"Poechlauer P.","year":"2012","journal-title":"Chim. Oggi.\/Chem. Today"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm2006029"},{"key":"e_1_2_9_4_1","first-page":"53","volume-title":"Understanding the Principles of Organic Chemistry: A Laboratory Course","author":"Pedersen S. 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