{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:36:40Z","timestamp":1762508200052,"version":"build-2065373602"},"reference-count":51,"publisher":"Wiley","issue":"72","license":[{"start":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T00:00:00Z","timestamp":1606176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2020,12,23]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Owing to their high surface area, high concentration of active metal sites, and water stability, zirconium(VI)\u2010based metal\u2013organic frameworks (Zr\u2010MOFs) have shown excellent activity in the hydrolysis of organophosphorus nerve agents (OPNs). In this regard, for the first time, two topologically different Zr\u2010MOFs (Zr\u2010fcu\u2010tmuc and Zr\u2010bcu\u2010tmuc, constructed from the same organic and inorganic building blocks; fcu=face\u2010centered cubic, bcu=body\u2010centered cubic) have been rationally chosen to investigate the effect of network topology on the catalytic hydrolysis of the nerve agent simulant, dimethyl 4\u2010nitrophenyl phosphate (DMNP). A remarkable enhancement in the hydrolysis rate of DMNP was observed with Zr\u2010bcu\u2010tmuc, reducing the half\u2010life more than three\u2010fold compared with Zr\u2010fcu\u2010tmuc. Greater accessibility of the active Zr<jats:sup>VI<\/jats:sup> sites in the 8\u2010connected bcu net compared with the 12\u2010connected fcu leads to a faster hydrolysis of DMNP on Zr\u2010bcu\u2010tmuc. Interestingly, the higher activity of Zr\u2010bcu\u2010tmuc was also confirmed by its higher fluorescence sensitivity towards DMNP (limit of detection (LOD)=0.557\u2005\u03bc<jats:sc>m<\/jats:sc>) compared with Zr\u2010fcu\u2010tmuc (LOD=1.09\u2005\u03bc<jats:sc>m<\/jats:sc>). The results show that controlling the desired topology of Zr\u2010MOFs is a useful strategy for improving their performance in the detection and catalytic detoxification of OPNs.<\/jats:p>","DOI":"10.1002\/chem.202002412","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T18:20:38Z","timestamp":1596651638000},"page":"17437-17444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Function\u2013Topology Relationship in the Catalytic Hydrolysis of a Chemical Warfare Simulant in Two Zr\u2010MOFs"],"prefix":"10.1002","volume":"26","author":[{"given":"Hosein","family":"Ghasempour","sequence":"first","affiliation":[{"name":"Department of Chemistry Faculty of Sciences Tarbiat Modares University  14115175 Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1828-7287","authenticated-orcid":false,"given":"Ali","family":"Morsali","sequence":"additional","affiliation":[{"name":"Department of Chemistry Faculty of Sciences Tarbiat Modares University  14115175 Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,24]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2005.06.011"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(99)70229-5"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X11311030006"},{"key":"e_1_2_7_4_1","unstructured":"Fassihi Farnaz (27 October 2002)In Iran grim reminders of Saddam\u2032s arsenal New Jersey Star-Ledger."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.341.6150.1050"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1017\/S7777777702000043","volume":"1","author":"Katzenstein P. J.","year":"2002","journal-title":"Dialogue IO"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2007.111930"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/b602769e"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi101056m"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007750100209"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2009.09.018"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/ic0107025"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja405495u"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cssc.200800246"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/b807080f"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8TA03306D"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.poly.2018.05.009"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201902229"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201902229"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201804149"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.poly.2020.114422"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201402895"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2016.11.008"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-814633-0.00001-6"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201603976"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)42207-7"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC03398E"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.5b01867"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4SC03613A"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201502155"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201502155"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c03404"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00828"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micromeso.2019.01.046"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.0c00986"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201204806"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201204806"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b07050"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.6b04835"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2012.01.104"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b18478"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b03594"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201307520"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201307520"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.8b03641"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201203267"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201208885"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201208885"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.5b01175"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6CE00108D"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2019.127341"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fchem.202002412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202002412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/chem.202002412","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202002412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T21:30:14Z","timestamp":1760304614000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.202002412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,24]]},"references-count":51,"journal-issue":{"issue":"72","published-print":{"date-parts":[[2020,12,23]]}},"alternative-id":["10.1002\/chem.202002412"],"URL":"https:\/\/doi.org\/10.1002\/chem.202002412","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"type":"print","value":"0947-6539"},{"type":"electronic","value":"1521-3765"}],"subject":[],"published":{"date-parts":[[2020,11,24]]},"assertion":[{"value":"2020-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}