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Herein, the first example of a radical\u2010generating system is reported that does not require any photoirradiation, radical initiators, or preactivated substrates. The oxidative C\u2212C\u2010bond cleavage of 2\u2010substituted cyclohexanones was achieved using an azolium salt and a hydroquinone as co\u2010catalysts. A catalytic mechanism was proposed based on the results of diffusion\u2010ordered spectroscopy and cyclic voltammetry measurements, as well as computational studies.<\/jats:p>","DOI":"10.1002\/chem.202004943","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T12:57:03Z","timestamp":1606827423000},"page":"2633-2637","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Azolium\/Hydroquinone Organo\u2010Radical Co\u2010Catalysis: Aerobic C\u2212C\u2010Bond Cleavage in Ketones"],"prefix":"10.1002","volume":"27","author":[{"given":"Yuya","family":"Nakatsuji","sequence":"first","affiliation":[{"name":"Graduate School of Pharmaceutical Sciences Kyoto University  46-29 Shimoadachi-cho, Yoshida Sakyo-ku Kyoto 606-8501 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