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The reaction tolerates numerous functional groups including free alcohols, esters, amides, and it can be applied also to the \u03b1\u2010desulfonylation of ketones. In addition, a one\u2010pot desulfonylative alkylation is demonstrated. Preliminary mechanistic studies indicate a catalyst\u2010dependent mechanism involving a homolytic C\u2212S cleavage.<\/jats:p>","DOI":"10.1002\/chem.202005400","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T12:58:08Z","timestamp":1612529888000},"page":"6178-6182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["A Titanium\u2010Catalyzed Reductive \u03b1\u2010Desulfonylation"],"prefix":"10.1002","volume":"27","author":[{"given":"Christoph","family":"Kern","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Organische Chemie Albert-Ludwigs-Universit\u00e4t Freiburg  Albertstr. 21 79104 Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Selau","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Organische Chemie Albert-Ludwigs-Universit\u00e4t Freiburg  Albertstr. 21 79104 Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8320-4353","authenticated-orcid":false,"given":"Jan","family":"Streuff","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Organische Chemie Albert-Ludwigs-Universit\u00e4t Freiburg  Albertstr. 21 79104 Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"Selected recent reviews:"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr800309r"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200906340"},{"key":"e_1_2_2_3_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200906340"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1560444"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201902019"},{"key":"e_1_2_2_6_1","unstructured":"Selected reviews:"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(99)00600-6"},{"key":"e_1_2_2_8_2","first-page":"367","volume-title":"Organic Reactions, Vol. 72","author":"Alonso D. 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