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A rhodamine 6G\u2010aminomethylanthracene\u2010linked donor\u2010acceptor molecule (<jats:bold>RA<\/jats:bold>) is designed and synthesized for demonstrating wavelength\u2010dependent functionalities as follows; (i) <jats:bold>RA<\/jats:bold> acts as a conventional fluorogenic <jats:sup>1<\/jats:sup>O<jats:sub>2<\/jats:sub> sensor molecule like the commercially available reagent, singlet oxygen sensor green (SOSG), when it absorbs ultraviolet (UV)\u2010visible light and reacts with <jats:sup>1<\/jats:sup>O<jats:sub>2<\/jats:sub>. (ii) <jats:bold>RA<\/jats:bold> acts as a temporally controlled <jats:sup>1<\/jats:sup>O<jats:sub>2<\/jats:sub> sensing reagent under the longer wavelength (\u223c700\u2005nm) photosensitization. <jats:bold>RA<\/jats:bold> enters an intermediate state after capturing <jats:sup>1<\/jats:sup>O<jats:sub>2<\/jats:sub> and does not become strongly fluorescent until it is exposed to UV, blue, or green light. (iii) <jats:bold>RA<\/jats:bold> acts as an efficient photosensitizer to generate <jats:sup>1<\/jats:sup>O<jats:sub>2<\/jats:sub> under green light illumination. The spin\u2010orbit charge transfer mediated intersystem crossing (SOCT\u2010ISC) process achieves this function, and <jats:bold>RA<\/jats:bold> shows a potential cancer\u2010killing effect on pancreatic cancer cells. The wavelength\u2010switchable functionalities in <jats:bold>RA<\/jats:bold> offer to promise molecular tools to apply <jats:sup>1<\/jats:sup>O<jats:sub>2<\/jats:sub> in a spatiotemporal manner.<\/jats:p>","DOI":"10.1002\/chem.202202014","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T22:20:00Z","timestamp":1665613200000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Excitation\u2010Wavelength\u2010Dependent Functionalities of Temporally Controlled Sensing and Generation of Singlet Oxygen by a Photoexcited State Engineered Rhodamine 6G\u2010Anthracene Conjugate"],"prefix":"10.1002","volume":"28","author":[{"given":"Hanjun","family":"Zhao","sequence":"first","affiliation":[{"name":"Graduate School of Environmental Science Hokkaido University  N10, W5 Sapporo 060-0810 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9469-6253","authenticated-orcid":false,"given":"Yuta","family":"Takano","sequence":"additional","affiliation":[{"name":"Graduate School of Environmental Science Hokkaido University  N10, W5 Sapporo 060-0810 Japan"},{"name":"Research Institute for Electronic Science Hokkaido University  N20, W10 Sapporo 001-0020 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devika","family":"Sasikumar","sequence":"additional","affiliation":[{"name":"Graduate School of Environmental Science Hokkaido University  N10, W5 Sapporo 060-0810 Japan"},{"name":"Research Institute for Electronic Science Hokkaido University  N20, W10 Sapporo 001-0020 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Miyatake","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine and Graduate School of Medicine Hokkaido University  N15, W7 Sapporo 060-8638 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasudevanpillai","family":"Biju","sequence":"additional","affiliation":[{"name":"Graduate School of Environmental Science Hokkaido University  N10, W5 Sapporo 060-0810 Japan"},{"name":"Research Institute for Electronic Science Hokkaido University  N20, W10 Sapporo 001-0020 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-8545(02)00034-6"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21030342"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b02396"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CP05025H"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar010086g"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201501131"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201501131"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201806881"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201806881"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC06231A"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/b912527m"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC08563G"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1NA00427A"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja504279r"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp406638g"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cptc.201700046"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12039-018-1578-1"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-15054-4"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/wcms.83"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.1c02071"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b00551"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b00551"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2016.06.025"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201501131"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201501131"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2016.06.025"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42004-021-00581-4"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0901557"},{"key":"e_1_2_8_26_1","volume-title":"Gaussian 16, Revision C.01","author":"Frisch D. 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