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The key processes involved are a ring\u2010closing metathesis leading to a bridged alkene\u2010tethered ketone and its subsequent Fe<jats:sup>III<\/jats:sup>\u2010mediated metal\u2010hydride atom transfer (MHAT) transannular cyclization. This synthetic method, implying an irreversible addition of a carbon\u2010centered radical upon a ketone by means of a hydrogen atom transfer upon the alkoxy radical intermediate, was also applied in the synthesis of <jats:italic>trans<\/jats:italic>\u2010fused hydrindanols structurally related to botrydial compounds.<\/jats:p>","DOI":"10.1002\/chem.202203286","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T10:15:49Z","timestamp":1671531349000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Four\u2010Step Synthesis of (\u2212)\u20104\u2010<i>epi<\/i>\u2010Presilphiperfolan\u20108<i>\u03b1<\/i>\u2010ol by Intramolecular Iron Hydride Atom Transfer\u2010Mediated Ketone\u2010Alkene Coupling and Studies to Access <i>trans<\/i>\u2010Hydrindanols with a Botryane Scaffold"],"prefix":"10.1002","volume":"29","author":[{"given":"Mar","family":"Saladrigas","sequence":"first","affiliation":[{"name":"Laboratori de Qu\u00edmica Org\u00e0nica Facultat de Farm\u00e0cia, IBUB Universitat de Barcelona  Av. 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