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Nevertheless, they are also a kind of quaternary ammonium compounds (QACs) that possess amphipathic properties. The unique chemical and physical properties of 1,2,4\u2010triazolium salts have received significant attention from scientists focusing on the development of novel bioactive molecules as pesticides and medicines. It is timely and meaningful to summarize the bioactivities of 1,2,4\u2010triazolium salt derivatives against various bacteria, fungi, cancer cells, and other pathogens in the past 30\u2005years. Meanwhile, the structure\u2010activity relationship (SAR) of 1,2,4\u2010triazolium salts was also summarized. Finally, our perspective on the future development and applications of triazolium salts as agrichemicals or human drugs is presented.<\/jats:p>","DOI":"10.1002\/chem.202203661","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T23:06:01Z","timestamp":1678835161000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Bioactivities of Triazolium\u2010Based <i>N<\/i>\u2010Heterocyclic Carbene Salts"],"prefix":"10.1002","volume":"29","author":[{"given":"Jia","family":"Song","sequence":"first","affiliation":[{"name":"National Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide and Agricultural Bioengineering Ministry of Education Guizhou University Huaxi District  Guiyang 550025 P. R. 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