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This tandem process involves the in\u2005situ generation of \u03b1\u2010amino ketones via the nucleophilic substitution of \u03b1\u2010bromoketones with amines and the Ir\u2010catalyzed asymmetric hydrogenation of ketone intermediates to provide diverse enantiomerically enriched \u03b2\u2010amino alcohols. 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