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This approach was demonstrated to be highly versatile in producing various types of imines, including symmetric and unsymmetric imines, by exploring the impact of different substituents on the benzene ring of the arylamine. Additionally, the method was specifically applied to modify N\u2010terminal phenylalanine residues and was found to be successful in the photoelectrochemical cross\u2010coupling reaction between NH<jats:sub>2<\/jats:sub>\u2010Phe\u2010OMe and aryl methylamines, leading to the synthesis of phenylalanine\u2010containing imines. Therefore, this technique would present a convenient and efficient platform for synthesizing imines, with promising applications in chemical biology, drug development, and organic synthesis.<\/jats:p>","DOI":"10.1002\/chem.202301379","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T01:32:56Z","timestamp":1689125576000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Versatile Synthesis of Symmetric and Unsymmetric Imines via Photoelectrochemical Catalysis: Application to N\u2010Terminal Modification of Phenylalanine"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9399-8284","authenticated-orcid":false,"given":"Chien\u2010Wei","family":"Chiang","sequence":"first","affiliation":[{"name":"Department of Chemistry Soochow University  No.70, Linhsi Road Shihlin District Taipei 111002 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