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The reaction shows a broad substrate scope including cyclic and acyclic siloxydienes derived from ketones, aldehydes, and esters, which are converted to 1,8\u2010dicarbonyl compounds under mild catalytic reaction conditions in 19\u201389\u2009% yield across 30 examples. The method is suitable for the coupling of sterically demanding carbon centers, including the formation of vicinal quaternary centers. Conceptually, the dienol ether serves as a precursor to a conjugated radical cation, which undergoes highly site selective \u03b3\u2010dimerization reactions. The \u03b3\u2010\u03b3 dimerization strategy is applied to the synthesis of a bioactive analogue of honokiol.<\/jats:p>","DOI":"10.1002\/chem.202302901","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:14:38Z","timestamp":1698711278000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Iron\u2010Catalyzed Gamma\u2010Gamma Dimerization of Siloxydienes"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2444-7168","authenticated-orcid":false,"given":"Daria","family":"Galaktionova","sequence":"first","affiliation":[{"name":"Department of Chemistry University of Illinois-Chicago  845 West Taylor St Chicago IL 60607 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoguang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Illinois-Chicago  845 West Taylor St Chicago IL 60607 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Illinois-Chicago  845 West Taylor St Chicago IL 60607 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7005-3322","authenticated-orcid":false,"given":"Justin T.","family":"Mohr","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Illinois-Chicago  845 West Taylor St Chicago IL 60607 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,4]]},"reference":[{"key":"e_1_2_9_1_1","unstructured":"\u00a0"},{"key":"e_1_2_9_2_2","doi-asserted-by":"crossref","unstructured":"Y.Ito T. 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