{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T18:04:06Z","timestamp":1782756246793,"version":"3.54.5"},"reference-count":57,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21871293 and 22071264"],"award-info":[{"award-number":["21871293 and 22071264"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2024,4,25]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this paper, Pd\u2010catalyzed [4+2] decarboxylative cycloaddition of 4\u2010vinylbenzodioxinones with barbiturate\u2010derived alkenes has been developed, leading to various spirobarbiturate\u2212chromane derivatives in high yields with excellent diastereo\u2010 and enantioselectivities. The scale\u2010up reaction and further derivation of the product were demonstrated. A plausible reaction mechanism was also proposed.<\/jats:p>","DOI":"10.1002\/chem.202400302","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T08:19:11Z","timestamp":1708503551000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Palladium\u2010Catalyzed Enantioselective [4+2] Cycloaddition of 4\u2010Vinylbenzodioxinones with Barbiturate\u2010Derived Alkenes: Con\u2010struction of Chiral Spirobarbiturate\u2212Chromanes"],"prefix":"10.1002","volume":"30","author":[{"given":"Yi","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Chemistry and Innovation Center of Pesticide Research China Agricultural University  2 West Yuanmingyuan Road Beijing 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxia","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Innovation Center of Pesticide Research China Agricultural University  2 West Yuanmingyuan Road Beijing 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Innovation Center of Pesticide Research China Agricultural University  2 West Yuanmingyuan Road Beijing 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Innovation Center of Pesticide Research China Agricultural University  2 West Yuanmingyuan Road Beijing 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochun","family":"Huyang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Innovation Center of Pesticide Research China Agricultural University  2 West Yuanmingyuan Road Beijing 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Food Science and Technology Chinese Academy of Agricultural Sciences  Beijing 100193 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7356-4283","authenticated-orcid":false,"given":"Hongchao","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Innovation Center of Pesticide Research China Agricultural University  2 West Yuanmingyuan Road Beijing 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"key":"e_1_2_8_1_1","unstructured":"\u00a0"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1039\/np9860300465"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00105a040"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm401007p"},{"key":"e_1_2_8_5_1","unstructured":"\u00a0"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2725(08)60921-6"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.2174\/1385272824666200110094457"},{"key":"e_1_2_8_8_1","unstructured":"For selected reviews see:"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr1002744"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1380170"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201702486"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201805009"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.7b03346"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24213930"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.adomc.2019.02.002"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201801575"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0OB00458H"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.0c00152"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00160"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1715-7413"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS00897H"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202101887"},{"key":"e_1_2_8_23_1","unstructured":"For selected examples in recent 5\u2005years see:"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-020-0503-7"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201905993"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202005313"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202117215"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c03102"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b00868"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b03582"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b12095"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b04590"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915021"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-019-0387-3"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c11504"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.1c01724"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202102061"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202113558"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202111376"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2023.108297"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202002765"},{"key":"e_1_2_8_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202117635"},{"key":"e_1_2_8_43_2","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC00112A"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201805876"},{"key":"e_1_2_8_45_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c11535"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201909158"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-019-0412-9"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202111708"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202102842"},{"key":"e_1_2_8_50_1","unstructured":"\u00a0"},{"key":"e_1_2_8_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.8b01268"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202002765"},{"key":"e_1_2_8_53_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c02508"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.202200160"},{"key":"e_1_2_8_55_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.3c02242"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3CC06012H"},{"key":"e_1_2_8_57_1","unstructured":"CCDC 2291804 for the compounds3\u2009jacontains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre viawww.ccdc.cam.ac.uk\/data_request\/cif."}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202400302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T14:59:01Z","timestamp":1760281141000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.202400302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,7]]},"references-count":57,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2024,4,25]]}},"alternative-id":["10.1002\/chem.202400302"],"URL":"https:\/\/doi.org\/10.1002\/chem.202400302","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,7]]},"assertion":[{"value":"2024-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202400302"}}