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However, gases are significantly more challenging to safely handle than liquids and solids. Herein, we review the use of porous materials, such as metal\u2010organic frameworks (MOFs), zeolites, and silicas, to adsorb medicinally relevant gases and facilitate their handling as solids. Specific topics include the use of MOFs and zeolites to deliver H<jats:sub>2<\/jats:sub>S for therapeutic applications, <jats:sup>129<\/jats:sup>Xe for magnetic resonance imaging, O<jats:sub>2<\/jats:sub> for the treatment of cancer and hypoxia, and various gases for use in organic synthesis. 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