{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T16:46:29Z","timestamp":1776617189560,"version":"3.51.2"},"reference-count":34,"publisher":"Wiley","issue":"69","license":[{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22278244"],"award-info":[{"award-number":["22278244"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["D20015"],"award-info":[{"award-number":["D20015"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2024AFB016"],"award-info":[{"award-number":["2024AFB016"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2024,12,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A straightforward asymmetric transfer hydrogenation for accessing enantiomerically enriched secondary benzyl alcohols involving free phenolic hydroxyl group(s) under mild conditions was developed. Various of optical pure aryl alcohols with a remarkable functional group compatibility were achieved with 78\u2009%\u201397\u2009% yields, 84\u2009%\u2013&gt;99\u2009% ee's and up to 10 000 TON. This rhodium\u2010catalyzed reaction could be performed in a gram\u2010scale without loss of the efficiency. Furthermore, the synthetic utility has also been demonstrated in the asymmetric synthesis of (<jats:italic>S<\/jats:italic>)\u2010adrenaline and (<jats:italic>S<\/jats:italic>)\u2010phenylephrine.<\/jats:p>","DOI":"10.1002\/chem.202403055","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T04:55:40Z","timestamp":1727067340000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Rhodium\u2010Catalyzed Asymmetric Transfer Hydrogenation of Aryl Ketones Involving Free Phenolic Hydroxyl Group(s)"],"prefix":"10.1002","volume":"30","author":[{"given":"Kedi","family":"Chang","sequence":"first","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruilong","family":"Chou","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinke","family":"Yu","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linhong","family":"Zuo","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qixing","family":"Liu","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5700-0608","authenticated-orcid":false,"given":"Xumu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Chemistry Academy for Advanced Interdisciplinary Studies and Shenzhen Grubbs Institute Southern University of Science and Technology  Shenzhen 518055 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Congcong","family":"Yin","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2710-9570","authenticated-orcid":false,"given":"Haifeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Natural Products Research and Development College of Biological and Pharmaceutical Sciences China Three Gorges University  Yichang 443002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,31]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1021\/jo00001a084","volume":"56","author":"Corey E. J.","year":"1991","journal-title":"J. Org. Chem."},{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1021\/jm00143a008","volume":"24","author":"Acheson R. M.","year":"1981","journal-title":"J. Med. Chem."},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"14222","DOI":"10.1021\/jacs.0c05446","volume":"142","author":"Mahmoodi N.","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ejps.2017.06.010","volume":"106","author":"Mayati A.","year":"2017","journal-title":"Eur. J. Pharm. Sci."},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"4978","DOI":"10.1021\/jm800710x","volume":"51","author":"Graaf C. D.","year":"2008","journal-title":"J. Med. Chem."},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jaci.2005.04.013","volume":"116","author":"Henderson W. R.","year":"2005","journal-title":"J. Allergy. Clin. Immun."},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1021\/jo00058a056","volume":"58","author":"Carpenter J. F.","year":"1993","journal-title":"J. Org. Chem."},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"102292","DOI":"10.1039\/C6RA22140H","volume":"6","author":"Xu Z.","year":"2016","journal-title":"RSC Adv."},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"3697","DOI":"10.1021\/acs.analchem.7b05186","volume":"90","author":"Shen H.","year":"2018","journal-title":"Anal. Chem."},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1016\/j.tetasy.2004.11.005","volume":"15","author":"Kumar P.","year":"2004","journal-title":"Tetrahedron: Asymmetry"},{"key":"e_1_2_7_11_1","volume":"475","author":"Islam M. M.","year":"2019","journal-title":"Mol. Cat."},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"11896","DOI":"10.1039\/C8NJ01745J","volume":"42","author":"Halder M.","year":"2018","journal-title":"New J. Chem."},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/cctc.201200617","volume":"5","author":"Sadhukhan A.","year":"2013","journal-title":"ChemCatChem"},{"key":"e_1_2_7_14_1","doi-asserted-by":"crossref","first-page":"2910","DOI":"10.1055\/s-0034-1378891","volume":"46","author":"Yuan M.-L.","year":"2014","journal-title":"Synthesis"},{"key":"e_1_2_7_15_1","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1039\/C7QO00237H","volume":"4","author":"Hu Y.","year":"2017","journal-title":"Org. Chem. Front."},{"key":"e_1_2_7_16_1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3390\/cells9020511","volume":"9","author":"Liu F.","year":"2020","journal-title":"Cells"},{"key":"e_1_2_7_17_1","first-page":"1121","volume":"11","author":"Hamadaa H.","year":"2016","journal-title":"Nat. Prod. Commun."},{"key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.procbio.2010.06.003","volume":"45","author":"Lin W.-D.","year":"2010","journal-title":"Process Biochem."},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.apcata.2013.03.032","volume":"459","author":"Das A.","year":"2013","journal-title":"Appl. Cata. A-Gen."},{"key":"e_1_2_7_20_1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.apcata.2012.06.042","volume":"439","author":"Kureshy R. I.","year":"2012","journal-title":"Appl. Cata. A-Gen."},{"key":"e_1_2_7_21_1","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1021\/cs2004467","volume":"1","author":"Kureshy R. I.","year":"2011","journal-title":"ACS Catal."},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1002\/adsc.201800267","volume":"360","author":"Yin C.","year":"2018","journal-title":"Adv. Synth. Catal."},{"key":"e_1_2_7_23_1","doi-asserted-by":"crossref","first-page":"4373","DOI":"10.1021\/ol020213o","volume":"4","author":"Hamada T.","year":"2002","journal-title":"Org. Lett."},{"key":"e_1_2_7_24_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1021\/ol062661s","volume":"9","author":"Ohkuma T.","year":"2007","journal-title":"Org. Lett."},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1021\/jo802350f","volume":"74","author":"Bisogno F. R.","year":"2009","journal-title":"J. Org. Chem."},{"key":"e_1_2_7_26_1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1021\/acs.orglett.7b03878","volume":"20","author":"Liu Q.","year":"2018","journal-title":"Org. Lett."},{"key":"e_1_2_7_27_1","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.1039\/C9CC09793G","volume":"56","author":"Wang F.","year":"2020","journal-title":"Chem. Commun."},{"key":"e_1_2_7_28_1","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1039\/D1GC00026H","volume":"23","author":"Zhang K.","year":"2021","journal-title":"Green Chem."},{"key":"e_1_2_7_29_1","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1021\/jacs.0c13273","volume":"143","author":"Wang F.","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"7794","DOI":"10.1038\/s41467-022-35124-5","volume":"13","author":"Wang F.","year":"2022","journal-title":"Nat. Commun."},{"key":"e_1_2_7_31_1","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1002\/adsc.202301186","volume":"366","author":"Yu P.","year":"2024","journal-title":"Adv. Synth. Catal."},{"key":"e_1_2_7_32_1","doi-asserted-by":"crossref","first-page":"4074","DOI":"10.1039\/D3GC04945K","volume":"26","author":"Yu P.","year":"2024","journal-title":"Green Chem."},{"key":"e_1_2_7_33_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.catcom.2015.01.012","volume":"62","author":"Echeverria P.-G.","year":"2015","journal-title":"Catal. Commun."},{"key":"e_1_2_7_34_1","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1002\/adsc.201400265","volume":"356","author":"Ki\u0161i\u0107 A.","year":"2014","journal-title":"Adv. Synth. Catal."}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202403055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:27:10Z","timestamp":1760297230000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.202403055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,31]]},"references-count":34,"journal-issue":{"issue":"69","published-print":{"date-parts":[[2024,12,10]]}},"alternative-id":["10.1002\/chem.202403055"],"URL":"https:\/\/doi.org\/10.1002\/chem.202403055","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,31]]},"assertion":[{"value":"2024-08-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202403055"}}