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To understand the molecular\u2010level behavior of the substrates and products at the <jats:italic>n<\/jats:italic>\u2010heptane\/IL interphase, atomistic molecular dynamics simulations were conducted and correlated with experimental observations. The thickness of the IL layer strongly influences the <jats:italic>Z\/E<\/jats:italic> ratio of the products in that a thin IL layer favors higher <jats:italic>Z\/E<\/jats:italic> ratios by confining the catalyst between the pore wall and the liquid\u2010liquid interphase whereas a thick IL layer favors formation of the <jats:italic>E<\/jats:italic>\u2010product and Ru\u2010hydride catalyzed isomerization reactions. Also, macrocyclization efficiency, expressed by the ratio of oligomers\/macromonocycle (O\/MMC), is influenced both by the flow rate and the thickness of the IL layer.<\/jats:p>","DOI":"10.1002\/chem.202403237","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T09:38:34Z","timestamp":1732527514000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Influence of Ionic Liquid Film Thickness and Flow Rate on Macrocyclization Efficiency and Selectivity in Supported Ionic Liquid\u2010Liquid Phase Catalysis"],"prefix":"10.1002","volume":"31","author":[{"given":"Marc","family":"H\u00f6gler","sequence":"first","affiliation":[{"name":"Institute of Thermodynamics and Thermal Process Engineering University of Stuttgart  Pfaffenwaldring 9 D-70569 Stuttgart 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