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The NXS\/TBHP reagent systems are demonstrated for\n                    <jats:italic>site<\/jats:italic>\n                    \u2010selective bromination and chlorination of the benzene\u2010core of quinoxalin\u20102(1\n                    <jats:italic>H<\/jats:italic>\n                    )\u2010ones. It is shown that the reagent system permits regioselective halogenation at the C7 position of the benzene core over the readily\u2010functionalized C3 position of quinoxalin\u20102(1\n                    <jats:italic>H<\/jats:italic>\n                    )\u2010ones under mild reaction conditions. We further show that terminal alkynes can be converted to\n                    <jats:italic>gem<\/jats:italic>\n                    \u2010dihaloketones in a facile manner by NXS\/TBHP. Mechanistically, single electron transfer between TBHP and NXS leads to instantaneous formation of electrophilic halogen radicals, which attack arenes and alkynes.\n                  <\/jats:p>","DOI":"10.1002\/chem.202404228","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T15:40:16Z","timestamp":1738856416000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["NXS\/TBHP as a Reagent System for Expedient Generation of Halogen Radicals:\n                    <i>Site<\/i>\n                    \u2010Selective Halogenation of Quinoxalin\u20102(1\n                    <i>H<\/i>\n                    )\u2010ones and Conversion of Terminal Alkynes to\n                    <i>gem<\/i>\n                    \u2010Dihaloketones"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4435-5401","authenticated-orcid":false,"given":"Navin","family":"Yadav","sequence":"first","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology  Kanpur 208016 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay Kumar","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology  Kanpur 208016 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debarghya","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology  Kanpur 208016 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9477-5015","authenticated-orcid":false,"given":"Jarugu Narasimha","family":"Moorthy","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology  Kanpur 208016 India"},{"name":"School of Chemistry Indian Institute of Science Education and Research Thiruvananthapuram  Trivandrum 695551 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"key":"e_1_2_6_1_1","unstructured":"\u00a0"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar9701777"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.2174\/138945010790711996"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ps.1829"},{"key":"e_1_2_6_5_1","unstructured":"\u00a0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24213839"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1GC01069G"},{"key":"e_1_2_6_8_1","unstructured":"\u00a0"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.200505158"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1039\/c1cs15129k"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.7b00285"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1705986"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/om900088z"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","unstructured":"R. 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