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This method is compatible with versatile functional groups: adamantyl, ether, alkynyl, and alkenyl, etc. Due to the mild nature of the reaction conditions, even the highly sensitive optically active aldehydes with an easily racemized <jats:italic>\u03b1<\/jats:italic>\u2010chiral center could be formed from optically active PMB ethers without racemization. Other protecting groups of hydroxyl group remained intact during the current aerobic oxidation. The catalytic protocol has been successfully applied to synthesis of (<jats:italic>R<\/jats:italic>)\u2010<jats:italic>tert<\/jats:italic>\u2010butyldimethylsilyl hept\u20101\u2010en\u20106\u2010yn\u20104\u2010yl ether, which is the key intermediate for the total synthesis of natural product, (\u2212)\u20106\u2010<jats:italic>O<\/jats:italic>\u2010methylcitreoisocoumarin.<\/jats:p>","DOI":"10.1002\/chem.202404754","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T03:33:11Z","timestamp":1739763191000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Catalytic Aerobic Oxidation of <i>p<\/i>\u2010Methoxybenzyl (PMB) Ethers to Aldehydes or Ketones"],"prefix":"10.1002","volume":"31","author":[{"given":"Qian","family":"Zhang","sequence":"first","affiliation":[{"name":"Research Center for Molecular Recognition and Synthesis, Department of Chemistry Fudan University  220 Handan Lu Shanghai 200433 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Qian","sequence":"additional","affiliation":[{"name":"Research Center for Molecular Recognition and Synthesis, Department of Chemistry Fudan University  220 Handan Lu Shanghai 200433 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2866-2431","authenticated-orcid":false,"given":"Shengming","family":"Ma","sequence":"additional","affiliation":[{"name":"Research Center for Molecular Recognition and Synthesis, Department of Chemistry Fudan University  220 Handan Lu Shanghai 200433 China"},{"name":"State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences  345 Lingling Lu Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"key":"e_1_2_8_1_1","volume-title":"Protective Groups in Organic Synthesis","author":"Wuts P. 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