{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:36:08Z","timestamp":1760315768966,"version":"build-2065373602"},"reference-count":30,"publisher":"Wiley","issue":"32","license":[{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22172164","21932005"],"award-info":[{"award-number":["22172164","21932005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008868","name":"Jiangsu Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["BX2023015"],"award-info":[{"award-number":["BX2023015"]}],"id":[{"id":"10.13039\/501100008868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2025,6,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bioethanol and furanics are currently prevailing additives to fossil\u2010based transportation fuels. With the objective to lift the longstanding limitations of these biofuel additives, this work reports for the first time the synthesis of 2\u2010ethoxy\u20102\u2010methyltetrahydrofuran (2\u2010EO\u20102\u2010MTHF) as a co\u2010upgraded fuel by reacting ethanol with 2\u2010methylfuran (2\u2010MF). The formation of 2\u2010EO\u20102\u2010MTHF is achieved through ethanol ethoxylation of 2\u2010MF, enabled by a reverse Ni(OH)<jats:italic><jats:sub>x<\/jats:sub><\/jats:italic>\/Ni catalyst under hydrogen pressure. Nickel hydroxide species over the Ni nanoparticles play a crucial role in activating ethanol and polarizing the partially hydrogenated dihydrofuran intermediates, favorably steering the reaction selectively toward the ethoxylation product. The reaction conditions, including pressure and temperature, are systematically optimized to enhance the yield of 2\u2010EO\u20102\u2010MTHF, and provide a means to beneficially tune the fuel compositions consisting mainly of 2\u2010EO\u20102\u2010MTHF and 2\u2010MTHF, both are high energy density molecules. Importantly, the reverse Ni(OH)<jats:italic><jats:sub>x<\/jats:sub><\/jats:italic>\u2010Ni catalyst allows a one\u2010pot process to accomplish consecutive partial hydrogenation of 2\u2010MF and ethanol ethoxylation. This work provides a practical strategy for upgrading biomass\u2010derived polar primary fuel molecules into more versatile fuels and chemicals.<\/jats:p>","DOI":"10.1002\/chem.202500567","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T22:44:27Z","timestamp":1745361867000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ni(OH)<i>x<\/i>\/Ni\u2010Catalyzed In Situ Hydrogenation and Ethanol Ethoxylation of 2\u2010Methylfuran for Renewable Biofuel Co\u2010Upgrading"],"prefix":"10.1002","volume":"31","author":[{"given":"Jun","family":"Shen","sequence":"first","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changhui","family":"Liang","sequence":"additional","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huixiang","family":"Li","sequence":"additional","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongxin","family":"Li","sequence":"additional","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songhai","family":"Xie","sequence":"additional","affiliation":[{"name":"Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian Liaoning 116023 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8292-1169","authenticated-orcid":false,"given":"Z. Conrad","family":"Zhang","sequence":"additional","affiliation":[{"name":"NERC Biomass, Changzhou University Changzhou Jiangsu 213164 China"},{"name":"Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Fudan University Shanghai 200433 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,3]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcatb.2023.123576"},{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.energy.2024.130360"},{"key":"e_1_2_9_1_3","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-019-0084-4"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS00039J"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.8b00971"},{"key":"e_1_2_9_2_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.rser.2014.07.003"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijhydene.2024.10.289"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.energy.2022.124688"},{"key":"e_1_2_9_3_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.rser.2007.07.011"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rser.2021.111265"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biombioe.2018.10.008"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.154955"},{"key":"e_1_2_9_5_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.fuel.2024.133799"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fuel.2022.126118"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.energyfuels.5b02674"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja01195a061"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo01143a022"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2023.157433"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2021.08.037"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-2738(01)00707-X"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1149\/1.1837437"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2cy20204b"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.enconman.2012.02.010"},{"key":"e_1_2_9_12_3","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.6b03494"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.141944"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8GC03938K"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0AN01327G"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcata.2022.118766"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c01276"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcata.2012.04.039"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202500567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:44:59Z","timestamp":1760273099000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.202500567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,3]]},"references-count":30,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2025,6,6]]}},"alternative-id":["10.1002\/chem.202500567"],"URL":"https:\/\/doi.org\/10.1002\/chem.202500567","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"type":"print","value":"0947-6539"},{"type":"electronic","value":"1521-3765"}],"subject":[],"published":{"date-parts":[[2025,5,3]]},"assertion":[{"value":"2025-02-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202500567"}}