{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:17:12Z","timestamp":1792675032745,"version":"4.5.0"},"reference-count":73,"publisher":"Wiley","issue":"35","license":[{"start":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T00:00:00Z","timestamp":1747872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007480","name":"Universidad de Castilla-La Mancha","doi-asserted-by":"publisher","award":["2022\u2010GRIN\u201034325"],"award-info":[{"award-number":["2022\u2010GRIN\u201034325"]}],"id":[{"id":"10.13039\/501100007480","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011698","name":"Junta de Comunidades de Castilla-La Mancha","doi-asserted-by":"publisher","award":["PRTR\u2010C17.I1"],"award-info":[{"award-number":["PRTR\u2010C17.I1"]}],"id":[{"id":"10.13039\/501100011698","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["PRTR\u2010C17.I1"],"award-info":[{"award-number":["PRTR\u2010C17.I1"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2025,6,23]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Metal complexation modulates the antioxidant properties of many flavonoids, including quercetin (QRT). However, competition between the antioxidant and autoxidation processes limits their longevity. This necessitates a deeper understanding of the fate of QRT phenoxy radicals following antioxidant activity. Here, we report on the formation of QRT\u2022Zr complexes and their photobehaviors, which account for the photochemical reactivity of the generated radicals. In methanol, N, N\u2010dimethylformamide, and water, the UV\u2010visible absorption spectra of the 1:1 and 1:2 complexes exhibit a significant bathochromic shift (50\u2013100\u00a0nm) and high global binding constants (1 \u2013 14\u00a0\u00d7 10<jats:sup>9<\/jats:sup> M<jats:sup>\u22122<\/jats:sup>). While the formation of charge\u2010transfer states through ligand\u2010to\u2010metal charge transfer in the ground state prevents the excited\u2010state intramolecular proton transfer that typically occurs in QRT, it leads to the generation of excited metal\u2010bound ligand radicals. We present details on the dynamics and further relaxation from femto to millisecond regimes of the excited complexes and generated species. The lifetimes of the formed radicals are considerably shorter than those of the free QRT radicals due to rapid back electron transfer, regenerating the neutral complexes. These findings will facilitate the design of other systems for antioxidant activity, photocatalysis, and various applications in chemistry, biochemistry, and biomedicine.<\/jats:p>","DOI":"10.1002\/chem.202500854","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T12:03:38Z","timestamp":1747051418000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Quercetin\u2022Zirconium Metal Complexes: Insights from Femto to Millisecond Photobehavior"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9474-821X","authenticated-orcid":false,"given":"Subhrakant","family":"Jena","sequence":"first","affiliation":[{"name":"Departamento de Qu\u00edmica F\u00edsica, Facultad de Ciencias Ambientales y Bioqu\u00edmica, and INAMOL Universidad de Castilla\u2010La Mancha  Avenida Carlos III Toledo 45071 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5400-4678","authenticated-orcid":false,"given":"Boiko","family":"Cohen","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica F\u00edsica, Facultad de Ciencias Ambientales y Bioqu\u00edmica, and INAMOL Universidad de Castilla\u2010La Mancha  Avenida Carlos III Toledo 45071 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2490-5034","authenticated-orcid":false,"given":"Maria Rosaria","family":"di Nunzio","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica F\u00edsica, Facultad de Ciencias Ambientales y Bioqu\u00edmica, and INAMOL Universidad de Castilla\u2010La Mancha  Avenida Carlos III Toledo 45071 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2247-7566","authenticated-orcid":false,"given":"Abderrazzak","family":"Douhal","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica F\u00edsica, Facultad de Ciencias Ambientales y Bioqu\u00edmica, and INAMOL Universidad de Castilla\u2010La Mancha  Avenida Carlos III Toledo 45071 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11112925"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-021-00233-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2023.1158198"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.06.010"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13091092"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/162750"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crphar.2023.100167"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13080922"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25225243"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29112573"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/pr11092771"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfutfo.2023.07.002"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.882458"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12061141"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-7847.194044"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.0c01818"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8825387"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom15010151"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.2c03291"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202001956"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1CP04690J"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(95)00011-L"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CP01779C"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp3033337"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201705635"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/278737a0"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC06143F"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC05268K"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3GC04595A"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202200916"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules191119180"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA05069C"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/00958972.2012.668617"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8877862"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24061123"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01202020"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(01)82392-8"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac60084a026"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1039\/an9709500781"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10562-022-04009-z"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceramint.2023.06.296"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.5b04867"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2022.140189"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep32152"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/poc.3684"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA16405B"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf060986h"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ica.2023.121673"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jics.2023.101059"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1872-1508(07)60071-0"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-9140(68)80012-8"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1039\/C0CS00062K"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201304157"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2007.07.041"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp053506i"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0162-0134(02)00469-5"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.poly.2005.04.019"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules190913643"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2012.02.007"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2023.215206"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2013.087"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9RA10154C"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CP00864B"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2023.122637"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1386-1425(01)00515-7"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-020-0430-7"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/hlca.201000227"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0CP00438C"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2005.10.009"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202108971"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2006.07.049"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(08)03408-3"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1039\/c1cp21039d"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202500854","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:52:19Z","timestamp":1760298739000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.202500854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,22]]},"references-count":73,"journal-issue":{"issue":"35","published-print":{"date-parts":[[2025,6,23]]}},"alternative-id":["10.1002\/chem.202500854"],"URL":"https:\/\/doi.org\/10.1002\/chem.202500854","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,22]]},"assertion":[{"value":"2025-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202500854"}}