{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:58:38Z","timestamp":1783421918348,"version":"3.54.6"},"reference-count":34,"publisher":"Wiley","issue":"30","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201011\u2010LABEX\u20100039"],"award-info":[{"award-number":["ANR\u201011\u2010LABEX\u20100039"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2025,5,27]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Herein, we report a general, efficient, and practical methodology for the macrocyclization of compounds based on the combination of a Cu\u2010catalyzed click\u2010and\u2010release reaction and a hydrophobic tag. The procedure allows the preparation of cyclic products of different sizes and with various functionalities without the need of purification.<\/jats:p>","DOI":"10.1002\/chem.202500860","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T12:40:51Z","timestamp":1744375251000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Sydnonimine\u2010based Click\u2010and\u2010Release Approach to Cyclic Products"],"prefix":"10.1002","volume":"31","author":[{"given":"Guillaume","family":"Force","sequence":"first","affiliation":[{"name":"CEA, INRAE D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS) SCBM Universit\u00e9 Paris Saclay  Gif\u2010sur\u2010Yvette 91191 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghao","family":"Feng","sequence":"additional","affiliation":[{"name":"CEA, INRAE D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS) SCBM Universit\u00e9 Paris Saclay  Gif\u2010sur\u2010Yvette 91191 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Audisio","sequence":"additional","affiliation":[{"name":"CEA, INRAE D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS) SCBM Universit\u00e9 Paris Saclay  Gif\u2010sur\u2010Yvette 91191 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Thu\u00e9ry","sequence":"additional","affiliation":[{"name":"CEA, CNRS, NIMBE Universit\u00e9 Paris\u2010Saclay  Gif\u2010sur\u2010Yvette 91191 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Schulz","sequence":"additional","affiliation":[{"name":"Institut de Chimie Mol\u00e9culaire et des Mat\u00e9riaux d'Orsay CNRS Universit\u00e9 Paris\u2010Saclay  Orsay 91400 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5461-329X","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Taran","sequence":"additional","affiliation":[{"name":"CEA, INRAE D\u00e9partement M\u00e9dicaments et Technologies pour la Sant\u00e9 (DMTS) SCBM Universit\u00e9 Paris Saclay  Gif\u2010sur\u2010Yvette 91191 France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"e_1_2_11_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1584"},{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.9b00149"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201807298"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b13178"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1CB00154J"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm400887j"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00657"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.8b00751"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-018-0187-4"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-018-0033-8"},{"key":"e_1_2_11_8_3","doi-asserted-by":"publisher","DOI":"10.1021\/ja805649f"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1729"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja8050519"},{"key":"e_1_2_11_9_3","doi-asserted-by":"publisher","DOI":"10.3390\/molecules18089512"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2OB01688E"},{"key":"e_1_2_11_11_1","first-page":"2847","volume":"9","author":"Ollivier N.","year":"2018","journal-title":"Nat. Chem."},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c10341"},{"key":"e_1_2_11_11_3","doi-asserted-by":"publisher","DOI":"10.1021\/ja9621105"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200801514"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.033"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201609427"},{"key":"e_1_2_11_13_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201705611"},{"key":"e_1_2_11_13_4","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC00798A"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201508416"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9OB01745C"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201708790"},{"key":"e_1_2_11_16_1","author":"Madegard L.","year":"2025","journal-title":"Angew. Chem. Int. Ed."},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1039\/D4SC04471A"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202302713"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcata.2016.10.004"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202101003"},{"key":"e_1_2_11_18_3","doi-asserted-by":"publisher","DOI":"10.1039\/D1QO00646K"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201801163"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.68.7.1428"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.202500860","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T21:01:39Z","timestamp":1760302899000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.202500860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,21]]},"references-count":34,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2025,5,27]]}},"alternative-id":["10.1002\/chem.202500860"],"URL":"https:\/\/doi.org\/10.1002\/chem.202500860","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,21]]},"assertion":[{"value":"2025-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202500860"}}