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BCP functionalization at the 2\u2010position is much less straightforward and currently under intense investigation. Herein, we report a synthetic route to 2\u2010methyl BCPs allowing for functionalization at the 1,3\u2010positions, with the novel 2\u2010methyl[1.1.1]propellane as a key intermediate. Next to an optimization for the synthesis of 2\u2010Me\u2010propellane, this work contains an investigation of its reactivity leading to 1,2\u2010disubstituted and 1,2,3\u2010trisubstituted BCP derivatives. Compared to nonsubstituted propellane, the synthesis of 2\u2010methyl propellane was lower\u2010yielding, and its ring\u2010opening reactions proceeded in similar or lower yields, with radical\u2010based reactions generally giving the best results. A preliminary study of selected physicochemical properties was conducted to assess the impact of the introduction of a bridge\u2010methyl group, showing an expected increase of about 0.5 log\n                    <jats:italic>P<\/jats:italic>\n                    units and featuring lower melting points.\n                  <\/jats:p>","DOI":"10.1002\/chem.202502396","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:39:02Z","timestamp":1760557142000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Methyl on the Bridge: 2\u2010Methyl Propellane as Precursor for 1,3\u2010Substituted 2\u2010Methylated Bicyclo[1.1.1]Pentanes"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2732-5193","authenticated-orcid":false,"given":"Sean R.","family":"Verschaeve","sequence":"first","affiliation":[{"name":"Department of Organic and Macromolecular Chemistry 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