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We report herein an efficient photochemical protocol for the oxidative cyclization of glycine derivatives to produce 2\u2010substituted benzoxazoles bearing ester or amide moieties. Cheap and commercially available 1,8\u2010dihydroxyanthraquinone serves as the organocatalyst in the presence of a nonprecious salt (CuI), while Kessil LED 427\u00a0nm is the source of irradiation. An extended substrate scope proves the generality of the method, which operates under mild conditions and in line with the principles of green chemistry. Direct infusion\u2010high resolution mass spectrometry studies supported the proposal of the reaction mechanism. Furthermore, ease derivatization of selected benzoxazole 2\u2010carboxylates\/carboxamides demonstrates their utility as versatile intermediates for the synthesis of a wide range of compounds, thereby highlighting the value and broader applicability of the new photochemical protocol.<\/jats:p>","DOI":"10.1002\/chem.202502901","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:54:42Z","timestamp":1762152882000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Sustainable Visible Light\u2010Mediated Synthesis of Benzoxazole 2\u2010Carboxylates\/Carboxamides"],"prefix":"10.1002","volume":"31","author":[{"given":"Anna\u2010Dimitra D.","family":"Gerogiannopoulou","sequence":"first","affiliation":[{"name":"Laboratory of Organic Chemistry Department of Chemistry National and Kapodistrian University of Athens Panepistimiopolis  Athens 15771 Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4669-2818","authenticated-orcid":false,"given":"Olga G.","family":"Mountanea","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Department of Chemistry National and Kapodistrian University of Athens Panepistimiopolis  Athens 15771 Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6552-5217","authenticated-orcid":false,"given":"Maria A.","family":"Theodoropoulou","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Department of Chemistry National and Kapodistrian University of Athens Panepistimiopolis  Athens 15771 Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4762-7682","authenticated-orcid":false,"given":"Christoforos G.","family":"Kokotos","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Department of Chemistry National and Kapodistrian University of Athens Panepistimiopolis  Athens 15771 Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3753-7082","authenticated-orcid":false,"given":"George","family":"Kokotos","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Department of Chemistry National and Kapodistrian University of Athens Panepistimiopolis  Athens 15771 Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,2]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41061-024-00477-6"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202400123"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00044-024-03190-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202100370"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241310807"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3675"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010716-104837"},{"key":"e_1_2_8_8_1","unstructured":"R. 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