{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:26:01Z","timestamp":1791523561094,"version":"4.3.4"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:00:00Z","timestamp":1766448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:00:00Z","timestamp":1766448000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22261132511"],"award-info":[{"award-number":["22261132511"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2026,2,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Dearomative addition reactions of indoles represent a prominent strategy for the synthesis of practically valuable indolines. However, implementing this approach typically requires prefunctionalization of the indole precursor with specific groups (e.g., alkynes, alkenes, or ketones) to facilitate the subsequent cyclization\u2010dearomatization step. In this work, we report a three\u2010component, thiol\u2010yne\u2010mediated dearomative vinylation of indoles that circumvents the need for preinstalling reactive fragments into the indole scaffold. The developed photoredox\u2010catalyzed thiol\u2010yne\u2010heteroarene reaction employs Boc\u2010protected indole\u20103\u2010carboxylates as effective terminating agents for the radical cascade.<\/jats:p>","DOI":"10.1002\/chem.202503346","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T07:00:08Z","timestamp":1766559608000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dearomative Vinylation of Indoles via Multicomponent Photoredox Thiol\u2010Yne\u2010Heteroarene Coupling Reaction"],"prefix":"10.1002","volume":"32","author":[{"given":"Andrey D.","family":"Kobelev","sequence":"first","affiliation":[{"name":"Zelinsky Institute of Organic Chemistry Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muzi","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikita S.","family":"Shlapakov","sequence":"additional","affiliation":[{"name":"Zelinsky Institute of Organic Chemistry Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia V.","family":"Burykina","sequence":"additional","affiliation":[{"name":"Zelinsky Institute of Organic Chemistry Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu\u2010Li","family":"You","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6447-557X","authenticated-orcid":false,"given":"Valentine P.","family":"Ananikov","sequence":"additional","affiliation":[{"name":"Zelinsky Institute of Organic Chemistry Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.3c01417"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201602771"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c16900"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja809842b"},{"key":"e_1_2_7_6_1","first-page":"1","volume-title":"Heterocyclic Scaffolds II: Reactions and Applications of Indoles","author":"Wu 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