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This method generates various C\u2010centered radicals, including methyl and acyl radicals, which undergo subsequent C\u2500C bond\u2010forming reactions. Density functional theory (DFT) calculations suggest that the selectivity of C\u2500C bond cleavage can be predicted according to the relative thermodynamic favorability among competing \u03b2\u2010scission pathways. Competition experiments showed that the \u03b2\u2010scission of a 3\u00b0 alcohol is suppressed in the presence of a carboxylic acid, where then decarboxylation of the carboxylic acid predominates. These results were attributed to the less favorable adsorption of the 3\u00b0 alcohol on TiO\n                    <jats:sub>2<\/jats:sub>\n                    relative to that of the carboxylic acid. By leveraging the adsorption\u2010controlled reaction kinetics, a synthetic strategy involving decarboxylation, and subsequent \u03b2\u2010scission was developed, which enabled the sequential incorporation of two different components into a substrate that contains a carboxylic acid and a 3\u00b0 alcohol moiety. This work thus showcases the unique reactivity and selectivity of the Pt\/TiO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010photocatalyzed \u03b2\u2010scission of 3\u00b0 alcohols, offering a new and distinctive addition to the toolkit of the modern organic chemist (186\/200).\n                  <\/jats:p>","DOI":"10.1002\/chem.202503629","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:07:00Z","timestamp":1772986020000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["\u03b2\u2010Scission of Tertiary Alcohols on a Platinum\u2010Loaded Titanium Dioxide Photocatalyst for C\u2500C Bond\u2010Forming Reactions"],"prefix":"10.1002","volume":"32","author":[{"given":"Shu","family":"Sakurai","sequence":"first","affiliation":[{"name":"Graduate School of Science Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sha","family":"Xue","sequence":"additional","affiliation":[{"name":"Graduate School of Science Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2535-9293","authenticated-orcid":false,"given":"Shogo","family":"Mori","sequence":"additional","affiliation":[{"name":"Integrated Research Consortium on Chemical Sciences (IRCCS) Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0749-2020","authenticated-orcid":false,"given":"Susumu","family":"Saito","sequence":"additional","affiliation":[{"name":"Graduate School of Science Nagoya University  Nagoya Japan"},{"name":"Integrated Research Consortium on Chemical Sciences (IRCCS) Nagoya University  Nagoya 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