{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:13:05Z","timestamp":1790244785479,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"25","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["Schu984\/12\u20132"],"award-info":[{"award-number":["Schu984\/12\u20132"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2026,7,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Malagasy frogs of the endemic family\n                    <jats:italic>Mantellinae<\/jats:italic>\n                    , among them\n                    <jats:italic>Gephyromantis granulatus<\/jats:italic>\n                    , have a unique feature: femoral glands that secrete volatile semiochemicals used for communication. Here, we report the structure elucidation, total synthesis, and determination of the absolute configuration of the main component of the femoral gland secretion of\n                    <jats:italic>G. granulatus<\/jats:italic>\n                    : granolide C. The structures of two further macrolides, granolides A and B, were also clarified. Structure elucidation was performed using GC\/MS, as NMR analysis was not possible due to the limited amount of available material. Various stereoisomers were synthesized using a flexible synthetic approach that enabled access to different substitution patterns found in granolides. Granolides A\u2013C are unique sesquiterpene macrocyclic lactones with ethyl branches instead of the common methyl branches \u2013 a feature that is rarely found in nature.\n                  <\/jats:p>","DOI":"10.1002\/chem.71139","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:11:29Z","timestamp":1779963089000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structure Elucidation and Total Synthesis of Granolides A\u2013C: Ethyl\u2010branched Sesquiterpenes From the Tropical Frog\n                    <i>Gephyromantis granulatus<\/i>"],"prefix":"10.1002","volume":"32","author":[{"given":"Johanna","family":"Kuhn","sequence":"first","affiliation":[{"name":"Technische Universit\u00e4t Braunschweig Institute of Organic Chemistry  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Vences","sequence":"additional","affiliation":[{"name":"Technische Universit\u00e4t Braunschweig Institute of Zoology  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schulz","sequence":"additional","affiliation":[{"name":"Technische Universit\u00e4t Braunschweig Institute of Organic Chemistry  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Life Counts: Eine globale Bilanz des Lebens","author":"Gleich M.","year":"2000"},{"key":"e_1_2_7_3_1","unstructured":"Amphibia Web (University of California 2026) Accessed 15 Februarywww.amphibiaweb.org."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0810821106"},{"key":"e_1_2_7_5_1","first-page":"130","article-title":"Two New Madagascan Frog Species of the Gephyromantis (Duboimantis) tandroka Complex from Northern Madagascar","volume":"36","author":"Scherz M. 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