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Meanwhile, visible light\u2010induced multicomponent organic reactions, featuring high atom economy and mild reaction conditions, have become an important strategy for building complex molecular architectures. Integrating these two strategies\u2014specifically, incorporating visible light\u2010induced alkyne\u2013carbonyl metathesis (ACM) into multicomponent reactions\u2014provides a new pathway for the efficient synthesis of functional aldehydes\/ketones while balancing reaction efficiency and atom economy. The review focuses on the research progress of visible light\u2010induced multicomponent reactions of nucleophiles with\n                    <jats:italic>p<\/jats:italic>\n                    \u2010quinone methide (\n                    <jats:italic>p<\/jats:italic>\n                    \u2010QM) intermediates in situ generated by ACM. Initially, this review mainly summarizes visible light\u2010induced multicomponent racemic coupling reactions with alkynes, quinones, and various nucleophiles. Thereafter, it further introduces the application of this strategy in the asymmetric synthesis of chiral compounds and discusses its substrate scope and reaction mechanisms in the construction of complex molecules. This review also highlights the current limitations and challenges within this field and provides an outlook on potential future research directions.\n                  <\/jats:p>","DOI":"10.1002\/chem.71306","type":"journal-article","created":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T16:07:18Z","timestamp":1782576438000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Visible Light\u2010Induced Alkyne\u2013Carbonyl Metathesis in Multicomponent Reactions"],"prefix":"10.1002","volume":"32","author":[{"given":"Pan","family":"Pan","sequence":"first","affiliation":[{"name":"Biomass Oligosaccharides Engineering Technology Research Center of Anhui Province Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions School of Chemical and Material Engineering Fuyang Normal University  Fuyang 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