{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:46:05Z","timestamp":1791899165988,"version":"4.3.4"},"reference-count":59,"publisher":"Wiley","issue":"38","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2026,10,13]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Cross\u2010dehydrogenative coupling (CDC) reactions are attractive and environmentally friendly ways to form new C\u2010C and other element\u2010element bonds. Here, we report the first CDC reactions triggered by a redox\u2010active guanidine reagent.\n                    <jats:italic>N<\/jats:italic>\n                    \u2010phenyltetrahydroisoquinoline and derivatives with electron\u2010donating and withdrawing substituents at the\n                    <jats:italic>N<\/jats:italic>\n                    \u2010phenyl group are reacted with nitromethane, dimethylmalonate and methylphenyl ketone in the presence of oxidized, dicationic 1,4\u2010bis(tetramethylguanidino)benzene as redox\u2010active guanidine reagent. The CDC products are obtained in good yield. The diprotonated 1,4\u2010bis(tetramethylguanidino)benzene by\u2010product can be easily separated from the product, and subsequently recycled through oxidation to the CDC reagent. The reaction mechanisms are discussed, and compared to the corresponding reactions with the high\u2010potential quinone 2,3\u2010dichloro\u20105,6\u2010dicyano\u20101,4\u2010benzoquinone (DDQ). The analysis discloses important advantages of redox\u2010active guanidine reagents compared to quinone reagents such as DDQ, arising from shorter lifetimes of radical intermediates.\n                  <\/jats:p>","DOI":"10.1002\/chem.71329","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:35:38Z","timestamp":1783100138000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cross\u2010Dehydrogenative Coupling Reactions With Redox\u2010Active Guanidine Reagents"],"prefix":"10.1002","volume":"32","author":[{"given":"Petra","family":"Walter","sequence":"first","affiliation":[{"name":"Anorganisch\u2010Chemisches Institut Ruprecht\u2010Karls\u2010Universit\u00e4t Heidelberg  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"H\u00fcbner","sequence":"additional","affiliation":[{"name":"Anorganisch\u2010Chemisches Institut 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