{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:33:26Z","timestamp":1793194406258,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","issue":"39","license":[{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC 22471211"],"award-info":[{"award-number":["NSFC 22471211"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"published-print":{"date-parts":[[2026,10,22]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Chiral phosphoric acid (CPA)\u2010catalyzed [3+2] cycloaddition of azonaphthalenes with 3\u2010vinylindoles is known to furnish C\u2010selective dihydrobenzo[e]indoles. We show here that installation of a substituent at C2 of the styrylindole partner unlocks a chemodivergent manifold in which both substrate sterics and catalyst structure govern C\u2010 versus N\u2010selective annulation. Under\n                    <jats:bold>A2<\/jats:bold>\n                    catalysis, minimally hindered substrates remain on the established C\u2010selective pathway, whereas more sterically demanding partners are diverted to a complementary N\u2010selective process. For these hindered substrates, switching to the anthryl\u2010substituted CPA\n                    <jats:bold>A4<\/jats:bold>\n                    reverses the chemoselectivity and restores efficient C\u2010selective cycloaddition. Across the two manifolds, structurally diverse annulation products are obtained in good to excellent yields and enantioselectivities. The N\u2010selective adducts further undergo DDQ\u2010mediated central\u2010to\u2010axial chirality conversion to furnish configurationally stable bisindole atropisomers in high yields and excellent chirality\u2010conversion percentages.\n                  <\/jats:p>","DOI":"10.1002\/chem.71337","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T08:57:13Z","timestamp":1783328233000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Substrate\u2010 and Catalyst\u2010Controlled Chemodivergent [3+2] Cycloaddition of 2\u2010Substituted 3\u2010Styrylindoles With Azonaphthalenes"],"prefix":"10.1002","volume":"32","author":[{"given":"Bo\u2010Bo","family":"Gou","sequence":"first","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry &amp; Materials Science Northwest University  Xi'an P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang\u2010Fan","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry &amp; Materials Science Northwest University  Xi'an P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Ming","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry &amp; Materials Science Northwest University  Xi'an P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gong\u2010Gu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry &amp; Materials Science Northwest University  Xi'an P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6745-5534","authenticated-orcid":false,"given":"Jie","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry &amp; Materials Science Northwest University  Xi'an P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6805-2961","authenticated-orcid":false,"given":"Ling","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry &amp; Materials Science Northwest University  Xi'an P. R. 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