{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T15:02:49Z","timestamp":1785337369606,"version":"3.55.0"},"reference-count":70,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Tris(indol\u20103\u2010yl)methanes were synthesized from indoles, CO\n                    <jats:sub>2<\/jats:sub>\n                    , and PhMe\n                    <jats:sub>2<\/jats:sub>\n                    SiH in the presence of BPh\n                    <jats:sub>3<\/jats:sub>\n                    in acetonitrile at 50\u00b0C. This is the first CO\n                    <jats:sub>2<\/jats:sub>\n                    fixation reaction forming the aliphatic methine (&gt;CH\u2500) group. The isotope\u2010labeling experiments clearly demonstrated that the carbon and hydrogen atoms of the methine group originated from carbon dioxide and dimethylphenylsilane, respectively. The mechanism for the multicomponent cascade reaction was elucidated by DFT calculations. One of the CO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010derived products, tris(4\u2010bromo\u20101\u2010methylindol\u20103\u2010yl)methane, underwent palladium\u2010catalyzed intramolecular cascade reactions for the selective formation of two novel polycyclic heteroaromatic compounds, where the methine C(\n                    <jats:italic>sp<\/jats:italic>\n                    <jats:sup>3<\/jats:sup>\n                    ) atom originating from CO\n                    <jats:sub>2<\/jats:sub>\n                    was converted into aromatic C(\n                    <jats:italic>sp<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    ) atoms. One is formally produced via double direct C\u2500H arylation, Wacker\u2010type oxidation, dehydrogenation, and debromination, while the other seems to be produced via the intramolecular homocoupling of aryl bromide, direct C\u2500H arylation, Wacker\u2010type oxidation, and dehydrogenation. Both of them are new intramolecular cascade reactions that are useful for the short\u2010step construction of nitrogen\u2010doped nanographenes. On the other hand, one of the CO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010derived products, tris(1\u2010pentylindol\u20103\u2010yl)methane, was converted into tris(1\u2010pentylindol\u20103\u2010yl)methylium methanesulfonate, which is a potential antitumor drug. This is the first derivatization of CO\n                    <jats:sub>2<\/jats:sub>\n                    to a cationic C(\n                    <jats:italic>sp<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    ) center.\n                  <\/jats:p>","DOI":"10.1002\/chem.71464","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T14:15:47Z","timestamp":1785334547000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Synthesis of Tris(indol\u20103\u2010yl)methanes From Indoles, CO\n                    <sub>2<\/sub>\n                    , and Dimethylphenylsilane With BPh\n                    <sub>3<\/sub>\n                    : Two\u2010Step Construction of \u03c0\u2010Conjugated Systems"],"prefix":"10.1002","author":[{"given":"Sha","family":"Li","sequence":"first","affiliation":[{"name":"Graduate School of Environmental, Life, Natural Science and Technology Okayama University  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So","family":"Saibara","sequence":"additional","affiliation":[{"name":"Graduate School of Environmental, Life, Natural Science and Technology Okayama University  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reito","family":"Yasui","sequence":"additional","affiliation":[{"name":"Graduate School of Environmental, Life, Natural Science and Technology Okayama University  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-7375","authenticated-orcid":false,"given":"Kazuto","family":"Takaishi","sequence":"additional","affiliation":[{"name":"Graduate School of Environmental, Life, Natural Science and Technology Okayama University  Okayama 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