{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:18:31Z","timestamp":1787847511760,"version":"build-2784847793"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Herein, we report an efficient and simple strategy to access diverse chiral\u2010at\u2010sulfur(VI) Br\u00f8nsted acids. Sulfonimidoyl chlorides or fluorides react with sulfonamides with inversion of configuration, producing chiral\u2010at\u2010sulfur sulfonimidamides containing an acidic NH group. Similarly, reactions of sulfonimidoyl chlorides with corresponding sulfonimidamides give access to\n                    <jats:italic>\n                      C\n                      <jats:sub>2<\/jats:sub>\n                    <\/jats:italic>\n                    \u2010symmetric chiral\u2010at\u2010sulfur Br\u00f8nsted acids. Finally, attaching sulfonimidamides to a 1,1\u2010bi\u20102\u2010naphthol (BINOL)\u2010derived phosphoryl chloride scaffold generates Br\u00f8nsted acids combining sulfur\u2010centered point chirality with BINOL axial chirality.\n                  <\/jats:p>","DOI":"10.1002\/chem.71623","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:20:18Z","timestamp":1787844018000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Synthesis of Chiral\u2010at\u2010Sulfur(VI) Sulfonimidamide Br\u00f8nsted Acids"],"prefix":"10.1002","author":[{"given":"Yu","family":"Han","sequence":"first","affiliation":[{"name":"Laboratory of Organic Chemistry Wageningen University  Wageningen the Netherlands"},{"name":"Key Laboratory of Phytochemical R&amp;D of Hunan Province and Key Laboratory of Chemical Biology &amp; Traditional Chinese Medicine Research of Ministry of Education Hunan Normal University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natassa","family":"Lional","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Wageningen University  Wageningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieuwertje E.","family":"Streefkerk","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Wageningen University  Wageningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse M. S.","family":"Goed","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Wageningen University  Wageningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9926-4377","authenticated-orcid":false,"given":"Bo","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Phytochemical R&amp;D of Hunan Province and Key Laboratory of Chemical Biology &amp; Traditional Chinese Medicine Research of Ministry of Education Hunan Normal University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5773-8506","authenticated-orcid":false,"given":"Han","family":"Zuilhof","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Wageningen University  Wageningen the Netherlands"},{"name":"College of Biological and Chemical Engineering Jiaxing University  Jiaxing China"},{"name":"School of Pharmaceutical Science and Technology Tianjin University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6420-211X","authenticated-orcid":false,"given":"Fedor M.","family":"Miloserdov","sequence":"additional","affiliation":[{"name":"Laboratory of Organic Chemistry Wageningen University  Wageningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1002\/anie.200353240","article-title":"Enantioselective Mannich\u2010Type Reaction Catalyzed by a Chiral Br\u00f8nsted Acid","volume":"43","author":"Akiyama T.","year":"2004","journal-title":"Angewandte Chemie International Edition"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"5356","DOI":"10.1021\/ja0491533","article-title":"Chiral Br\u00f8nsted Acid\u2010catalyzed Direct Mannich Reactions via Electrophilic Activation","volume":"126","author":"Uraguchi D.","year":"2004","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"4193","DOI":"10.1002\/anie.200600512","article-title":"Asymmetric Counteranion\u2010Directed Catalysis","volume":"45","author":"Mayer S.","year":"2006","journal-title":"Angewandte Chemie International Edition"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"4617","DOI":"10.1016\/S0040-4039(01)97544-6","article-title":"Enantiomeric Cyclic Binaphthyl Phosphoric Acids as Resolving Agents","volume":"12","author":"Jacques J.","year":"1971","journal-title":"Tetrahedron Letters"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/adsc.200900746","article-title":"Synthesis and Application of Polymer\u2010Supported Chiral Br\u00f8nsted Acid Organocatalysts","volume":"352","author":"Rueping M.","year":"2010","journal-title":"Advanced Synthesis & Catalysis"},{"key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"6495","DOI":"10.1002\/smll.201601455","article-title":"Circularly\u2010Polarized Luminescence (CPL) from Chiral AIE Molecules and Macrostructures","volume":"12","author":"Roose J.","year":"2016","journal-title":"Small"},{"key":"e_1_2_8_8_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2020.213329","article-title":"Chiral AIEgens \u2013 Chiral Recognition, CPL Materials and Other Chiral Applications","volume":"416","author":"Hu M.","year":"2020","journal-title":"Coordination Chemistry Reviews"},{"key":"e_1_2_8_9_1","doi-asserted-by":"crossref","first-page":"14255","DOI":"10.1021\/ja0207192","article-title":"Stereocartography:\u2009 A Computational Mapping Technique That Can Locate Regions of Maximum Stereoinduction around Chiral Catalysts","volume":"124","author":"Lipkowitz K. 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These data are provided free of charge by the joint Cambridge Crystallographic Data Centre and Fachinformationszentrum Karlsruhe Access Structures service."},{"key":"e_1_2_8_33_1","doi-asserted-by":"crossref","DOI":"10.1039\/9781849733069","volume-title":"Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013","author":"Favre H. 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