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Ferrocene\u2010mediated anodic decarboxylation generates acyl radicals, while cathodic reduction of nitroarenes enables the in situ generation of reactive nitrogen\u2010containing intermediates, thereby providing a direct route to C\u2500N bond formation without preforming aniline coupling partners. The transformation proceeds under mild, transition\u2010metal\u2010catalyst\u2010free conditions without stoichiometric chemical oxidants or reductants. A broad range of \u03b1\u2010ketoacids and nitroarenes are compatible with the reaction, affording the corresponding N\u2010aryl amides with excellent functional\u2010group tolerance. Mechanistic studies support the involvement of acyl and nitrogen\u2010containing intermediates in the amidation process.<\/jats:p>","DOI":"10.1002\/chem.71706","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:04:36Z","timestamp":1789646676000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Paired Electrochemical Decarboxylative Amidation of \u03b1\u2010Ketoacids With Nitroarenes"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4677-279X","authenticated-orcid":false,"given":"Yun","family":"Sa","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huirong","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology  Beijing China"},{"name":"Department of Pharmaceutical Sciences Inner Mongolia Medical University  Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1856-6323","authenticated-orcid":false,"given":"Duanyang","family":"Kong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology  Beijing China"},{"name":"Department of Pharmaceutical Sciences Inner Mongolia Medical University  Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c00754"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","DOI":"10.1002\/cmdc.202200526","article-title":"Phosphonate Derivatives of Paracetamol and Valproic Acid","volume":"18","author":"Ball\u00f3k R.","year":"2023","journal-title":"Chemmedchem"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.rechem.2023.101075","article-title":"Physicochemical Properties of Acedoben and Its Trifluoroacetamido Derivative","volume":"6","author":"Boldon J. 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