{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:45:41Z","timestamp":1792046741681,"version":"4.4.0"},"reference-count":61,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001852","name":"Indo-French Centre for the Promotion of Advanced Research","doi-asserted-by":"publisher","award":["69T08\u20102"],"award-info":[{"award-number":["69T08\u20102"]}],"id":[{"id":"10.13039\/501100001852","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Synthetic molecules that selectively transport anions across cellular membranes are an emerging class of therapeutics against cancer. Peptide\u2010derived transporters are attractive for cancer therapy due to their biocompatibility. A disulfide tether is employed here to position two anion\u2010binding hydrophobic tryptophan motifs in close proximity, thereby enhancing membrane insertion and anion selectivity. The tryptophan\u2010flanked cystine functions as an anion carrier with a preference toward nitrate and chloride ions. Reduction of the disulfide to the corresponding free thiol substantially decreases anion transport activity. In situ reduction in vesicular systems, is governed by the membrane uptake of the disulfide. This loss in activity upon reduction to the corresponding cysteine establishes a unique class of anionophores that is active as the oxidized species rather than one activated by reduction. Extension to a cellular context showed a depletion in viability of triple negative MDA\u2010MB\u2010231 breast cancer cells by 50\u00a0\u00b5M of the transporter compared with untransformed MCF\u201010A breast cells. In co\u2010cultures, the transporter shifted competitive viability in favor of the untransformed cells. These results establish cystine\u2010based peptides as a chemically programmable class of anionophores that translate potentially into cancer\u2010selective biological activity.<\/jats:p>","DOI":"10.1002\/chem.71794","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:11:25Z","timestamp":1792044685000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cystine as an Ionophore: Redox\u2010Controlled Anion Transport and Toxicity Toward Triple Negative Breast Cancer Cells"],"prefix":"10.1002","author":[{"given":"Smriti Subir","family":"Mukherjee","sequence":"first","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Bombay  Mumbai India"},{"name":"School of Chemistry Monash University  Clayton VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4144-3345","authenticated-orcid":false,"given":"Satyarthi","family":"Mishra","sequence":"additional","affiliation":[{"name":"Centre for Nanoscience &amp; Engineering (CeNSE) Division of Interdisciplinary Sciences Indian Institute of Science  Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6825-5777","authenticated-orcid":false,"given":"Tanja","family":"Junkers","sequence":"additional","affiliation":[{"name":"School of Chemistry Monash University  Clayton VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5215-9721","authenticated-orcid":false,"given":"Ramray","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology &amp; Genetics (DBG) Division of Biological Sciences Indian Institute of Science  Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1251-3527","authenticated-orcid":false,"given":"Nandita","family":"Madhavan","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Bombay  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1471-2407-13-63","article-title":"Rac3 Induces a Molecular Pathway Triggering Breast Cancer Cell Aggressiveness: Differences in MDA\u2010MB\u2010231 and MCF\u20107 Breast Cancer Cell Lines","volume":"13","author":"Gest C.","year":"2013","journal-title":"BMC Cancer"},{"key":"e_1_2_7_3_1","first-page":"4169","article-title":"Differential Suppression of Proliferation in MCF\u20107 and MDA\u2010MB\u2010231 Breast Cancer Cells Exposed to Alpha\u2010, Gamma\u2010 and Delta\u2010Tocotrienols is Accompanied by Altered Expression of Oxidative Stress Modulatory Enzymes","volume":"30","author":"Hsieh T. C.","year":"2010","journal-title":"Anticancer Research"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/his.14786","article-title":"An Update on the Pathological Classification of Breast Cancer","volume":"82","author":"Rakha E. A.","year":"2023","journal-title":"Histopathology"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"957","DOI":"10.3390\/cells8090957","article-title":"Mechanisms of Chemotherapy Resistance in Triple\u2010Negative Breast Cancer\u2014How We Can Rise to the Challenge","volume":"8","author":"Nedeljkovi\u0107 M.","year":"2019","journal-title":"Cells"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/s41419-022-04783-z","article-title":"Identification of a Novel Mechanism For Reversal Of Doxorubicin\u2010Induced Chemotherapy Resistance By TXNIP in Triple\u2010Negative Breast Cancer Via Promoting Reactive Oxygen\u2010Mediated DNA Damage","volume":"13","author":"Chen Y.","year":"2022","journal-title":"Cell Death & Disease"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0297260","article-title":"Exploring the Resistance Mechanism of Triple\u2010Negative Breast Cancer to Paclitaxel Through the scRNA\u2010seq Analysis","volume":"19","author":"Gao W.","year":"2024","journal-title":"PLoS ONE"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1039\/C7CS00159B","article-title":"Anion Transport and Supramolecular Medicinal Chemistry","volume":"46","author":"Gale P. A.","year":"2017","journal-title":"Chemical Society Reviews"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2024.102535","article-title":"Therapeutic Synthetic Anion Transporters","volume":"83","author":"Feo E.","year":"2024","journal-title":"Current Opinion in Chemical Biology"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s11426-022-1258-4","article-title":"Ion Transporters: Emerging Agents for Anticancer Therapy","volume":"65","author":"Yan T.","year":"2022","journal-title":"Science China Chemistry"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"9737","DOI":"10.1021\/jacs.3c01451","article-title":"A Benzohydrazide\u2010Based Artificial Ion Channel That Modulates Chloride Ion Concentration in Cancer Cells and Induces Apoptosis by Disruption of Autophagy","volume":"145","author":"Mondal A.","year":"2023","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"7558","DOI":"10.1021\/jacs.6b01723","article-title":"Chloride\u2010Mediated Apoptosis\u2010Inducing Activity of Bis(sulfonamide) Anionophores","volume":"138","author":"Saha T.","year":"2016","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nchem.2706","article-title":"A Synthetic Ion Transporter That Disrupts Autophagy and Induces Apoptosis by Perturbing Cellular Chloride Concentrations","volume":"9","author":"Busschaert N.","year":"2017","journal-title":"Nature Chemistry"},{"key":"e_1_2_7_14_1","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202318811","article-title":"Concentration\u2010Driven Evolution of Adaptive Artificial Ion Channels or Nanopores With Specific Anticancer Activities","volume":"63","author":"Chen Z.","year":"2024","journal-title":"Angewandte Chemie, International Edition"},{"key":"e_1_2_7_15_1","doi-asserted-by":"crossref","DOI":"10.1002\/chem.202403252","article-title":"Apoptosis\u2010Inducing Activity of a 2\u2010Hydroxyphenyl Benzamide\u2010Based Self\u2010Assembled Anion Channel","volume":"31","author":"Mondal A.","year":"2025","journal-title":"Chemistry \u2013 A European Journal"},{"key":"e_1_2_7_16_1","doi-asserted-by":"crossref","first-page":"7944","DOI":"10.1002\/anie.202000961","article-title":"A Glutathione Activatable Ion Channel Induces Apoptosis in Cancer Cells by Depleting Intracellular Glutathione Levels","volume":"59","author":"Malla J. A.","year":"2020","journal-title":"Angewandte Chemie, International Edition"},{"key":"e_1_2_7_17_1","doi-asserted-by":"crossref","first-page":"15319","DOI":"10.1021\/jacs.6b10592","article-title":"Enzyme\u2010Responsive Procarriers Capable of Transporting Chloride Ions Across Lipid and Cellular Membranes","volume":"138","author":"Choi Y. R.","year":"2016","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"17614","DOI":"10.1002\/anie.202006392","article-title":"Stimuli\u2010Responsive Cycloaurated \u201cOFF\u2010ON\u201d Switchable Anion Transporters","volume":"59","author":"Fares M.","year":"2020","journal-title":"Angewandte Chemie, International Edition"},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"8482","DOI":"10.1039\/C9CC04518J","article-title":"Tuning the Solubility of Ionophores: Glutathione\u2010Mediated Transport of Chloride Ions Across Hydrophobic Membranes","volume":"55","author":"Akhtar N.","year":"2019","journal-title":"Chemical Communications"},{"key":"e_1_2_7_20_1","doi-asserted-by":"crossref","first-page":"10107","DOI":"10.1039\/D0SC04417B","article-title":"Redox\u2010Controlled Chalcogen and Pnictogen Bonding: The Case of a Sulfonium\/Stibonium Dication as a Preanionophore for Chloride Anion Transport","volume":"11","author":"Park G.","year":"2020","journal-title":"Chemical Science"},{"key":"e_1_2_7_21_1","doi-asserted-by":"crossref","DOI":"10.1002\/chem.202301020","article-title":"An Amphiphilic Peptide Carrier for HCl Transport","volume":"29","author":"Kar S.","year":"2023","journal-title":"Chemistry \u2013 A European Journal"},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.xcrp.2024.102152","article-title":"Tuning pH\u2010Dependent Cytotoxicity in Cancer Cells by Peripheral Fluorine Substitution on Pseudopeptidic Cages","volume":"5","author":"Tapia L.","year":"2024","journal-title":"Cell Reports Physical Science"},{"key":"e_1_2_7_23_1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1039\/D3OB01826A","article-title":"A Chloride\u2010Responsive Molecular Switch: Driving Ion Transport and Empowering Antibacterial Properties","volume":"22","author":"Das S.","year":"2024","journal-title":"Organic & Biomolecular Chemistry"},{"key":"e_1_2_7_24_1","doi-asserted-by":"crossref","first-page":"10769","DOI":"10.1021\/jacs.0c02134","article-title":"Mediating K+\/H+ Transport on Organelle Membranes to Selectively Eradicate Cancer Stem Cells With a Small Molecule","volume":"142","author":"Shen F.\u2010F.","year":"2020","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","first-page":"4987","DOI":"10.1039\/D4OB00554F","article-title":"Bisindole\u2010Based Small Molecules as Transmembrane Anion Transporters and Potential Anticancer Agents","volume":"22","author":"Salunke S. B.","year":"2024","journal-title":"Organic & Biomolecular Chemistry"},{"key":"e_1_2_7_26_1","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202403314","article-title":"Responsive Anionophores With AND Logic Multi\u2010Stimuli Activation","volume":"63","author":"Ahmad M.","year":"2024","journal-title":"Angewandte Chemie, International Edition"},{"key":"e_1_2_7_27_1","doi-asserted-by":"crossref","DOI":"10.1002\/chem.202301412","article-title":"NAD(P)H:Quinone Acceptor Oxidoreductase 1 (NQO1) Activatable Salicylamide H+\/Cl\u2212Transporters","volume":"29","author":"Roy N. J.","year":"2023","journal-title":"Chemistry \u2013 A European Journal"},{"key":"e_1_2_7_28_1","doi-asserted-by":"crossref","first-page":"9397","DOI":"10.1038\/s41598-017-09645-9","article-title":"Indole\u2010Based Perenosins as Highly Potent HCl Transporters and Potential Anti\u2010Cancer Agents","volume":"7","author":"Jowett L. A.","year":"2017","journal-title":"Scientific Reports"},{"key":"e_1_2_7_29_1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/nrd2466","article-title":"The Nitrate\u2013Nitrite\u2013Nitric Oxide Pathway in Physiology and Therapeutics","volume":"7","author":"Lundberg J. O.","year":"2008","journal-title":"Nature Reviews Drug Discovery"},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1089\/ars.2018.7527","article-title":"Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism","volume":"30","author":"Somasundaram V.","year":"2019","journal-title":"Antioxidants & Redox Signaling"},{"key":"e_1_2_7_31_1","doi-asserted-by":"crossref","first-page":"R125","DOI":"10.1186\/bcr3319","article-title":"Ets\u20101 is a Transcriptional Mediator of Oncogenic Nitric Oxide Signaling in Estrogen Receptor\u2010Negative Breast Cancer","volume":"14","author":"Switzer C. H.","year":"2012","journal-title":"Breast Cancer Research"},{"key":"e_1_2_7_32_1","doi-asserted-by":"crossref","first-page":"8894","DOI":"10.1073\/pnas.0400453101","article-title":"Hypoxic Inducible Factor 1\u03b1, Extracellular Signal\u2010Regulated Kinase, and p53 are Regulated by Distinct Threshold Concentrations of Nitric Oxide","volume":"101","author":"Thomas D. D.","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"e_1_2_7_33_1","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.mattod.2015.11.025","article-title":"Tumor Microenvironment and Intracellular Signal\u2010Activated Nanomaterials for Anticancer Drug Delivery","volume":"19","author":"Mo R.","year":"2016","journal-title":"Materials Today"},{"key":"e_1_2_7_34_1","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1039\/D3NP00068K","article-title":"Verticillins: Fungal Epipolythiodioxopiperazine Alkaloids With Chemotherapeutic Potential","volume":"41","author":"Pierre H. C.","year":"2024","journal-title":"Natural Product Reports"},{"key":"e_1_2_7_35_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115452","article-title":"Insight Into Drug Sensitizing Effect of Diallyl Disulfide and Diallyl Trisulfide From Allium sativum L. on Paclitaxel\u2010Resistant Triple\u2010Negative Breast Cancer Cells","volume":"296","author":"Marni R.","year":"2022","journal-title":"Journal of Ethnopharmacology"},{"key":"e_1_2_7_36_1","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1021\/jacs.7b10227","article-title":"18 F\u2010Trifluoromethylation of Unmodified Peptides With 5\u2010 18 F\u2010(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate","volume":"140","author":"Verhoog S.","year":"2018","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_37_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1006\/abio.1994.1242","article-title":"Long\u2010Wavelength Chloride\u2010Sensitive Fluorescent Indicators","volume":"219","author":"Biwersi J.","year":"1994","journal-title":"Analytical Biochemistry"},{"key":"e_1_2_7_38_1","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1021\/bi00509a019","article-title":"Pyranine (8\u2010hydroxy\u20101,3,6\u2010pyrenetrisulfonate) as a Probe of Internal Aqueous Hydrogen Ion Concentration in Phospholipid Vesicles","volume":"20","author":"Clement N. R.","year":"1981","journal-title":"Biochemistry"},{"key":"e_1_2_7_39_1","doi-asserted-by":"crossref","first-page":"13089","DOI":"10.1021\/jacs.3c01623","article-title":"Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide\u2010Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides","volume":"145","author":"Chen Y.","year":"2023","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_40_1","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/s41563-025-02150-9","article-title":"Force Transmission is a Master Regulator of Mechanical Cell Competition","volume":"24","author":"Schoenit A.","year":"2025","journal-title":"Nature Materials"},{"key":"e_1_2_7_41_1","doi-asserted-by":"crossref","DOI":"10.1002\/jcp.70123","article-title":"Glycation\u2010Driven Impairment of Cytoskeletal Homeostasis and Viability Disables Glyoxalase\u2010Low Mesothelia From Resisting Cancer Colonization","volume":"241","author":"Mishra S.","year":"2026","journal-title":"Journal of Cellular Physiology"},{"key":"e_1_2_7_42_1","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202419800","article-title":"Engineered Reactive Oxygen Species (ROS)\u2010Responsive Artificial H\u00a0+\u00a0\/Cl\u2212Ion Channels for Targeted Cancer Treatment","volume":"64","author":"Jia C.","year":"2025","journal-title":"Angewandte Chemie, International Edition"},{"key":"e_1_2_7_43_1","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1469-7793.2001.0581e.x","article-title":"Chloride Channels Go Cell Cycling","volume":"532","author":"Nilius B.","year":"2001","journal-title":"The Journal of Physiology"},{"key":"e_1_2_7_44_1","doi-asserted-by":"crossref","first-page":"13301","DOI":"10.1074\/jbc.C400020200","article-title":"NAD(P)H Oxidase\u2010Derived H2O2 Signals Chloride Channel Activation in Cell Volume Regulation and Cell Proliferation","volume":"279","author":"Varela D.","year":"2004","journal-title":"Journal of Biological Chemistry"},{"key":"e_1_2_7_45_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0045340","article-title":"A Synthetic Chloride Channel Relaxes Airway Smooth Muscle of the Rat","volume":"7","author":"Yau K.\u2010H.","year":"2012","journal-title":"PLoS ONE"},{"key":"e_1_2_7_46_1","doi-asserted-by":"crossref","first-page":"14137","DOI":"10.1039\/D0CC05489E","article-title":"Biological Applications of Synthetic Anion Transporters","volume":"56","author":"Akhtar N.","year":"2020","journal-title":"Chemical Communications"},{"key":"e_1_2_7_47_1","doi-asserted-by":"crossref","DOI":"10.1038\/srep11298","article-title":"In Situ Characterizing Membrane Lipid Phenotype of Breast Cancer Cells Using Mass Spectrometry Profiling","volume":"5","author":"He M.","year":"2015","journal-title":"Scientific Reports"},{"key":"e_1_2_7_48_1","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1083\/jcb.201804161","article-title":"Glutathione Metabolism in Cancer Progression and Treatment Resistance","volume":"217","author":"Bansal A.","year":"2018","journal-title":"Journal of Cell Biology"},{"key":"e_1_2_7_49_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2025.167769","article-title":"Cell Competition as an Emerging Mechanism and Therapeutic Target in Cancer","volume":"1871","author":"Yang D.","year":"2025","journal-title":"Biochimica Et Biophysica Acta, Molecular Basis of Disease"},{"key":"e_1_2_7_50_1","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1016\/j.devcel.2024.06.022","article-title":"Autocrine Glutamate Signaling Drives Cell Competition in Drosophila","volume":"59","author":"Soares C. C.","year":"2024","journal-title":"Developmental Cell"},{"key":"e_1_2_7_51_1","doi-asserted-by":"crossref","first-page":"4487","DOI":"10.1158\/0008-5472.CAN-22-2217","article-title":"Cell Competition in Carcinogenesis","volume":"82","author":"Madan E.","year":"2022","journal-title":"Cancer Research"},{"key":"e_1_2_7_52_1","doi-asserted-by":"crossref","first-page":"3286","DOI":"10.1055\/s-2007-990800","article-title":"A Mild and Environmentally Benign Oxidation of Thiols to Disulfides","volume":"2007","author":"Kirihara M.","year":"2007","journal-title":"Synthesis"},{"key":"e_1_2_7_53_1","doi-asserted-by":"crossref","DOI":"10.1002\/anse.202300044","article-title":"The Lucigenin Assay: Measuring Anion Transport in Lipid Vesicles**","volume":"4","author":"Chvojka M.","year":"2024","journal-title":"Analysis & Sensing"},{"key":"e_1_2_7_54_1","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1038\/s41565-021-00915-2","article-title":"Foldamer\u2010Based Ultrapermeable and Highly Selective Artificial Water Channels That Exclude Protons","volume":"16","author":"Roy A.","year":"2021","journal-title":"Nature Nanotechnology"},{"key":"e_1_2_7_55_1","doi-asserted-by":"crossref","first-page":"4831","DOI":"10.1021\/acs.nanolett.2c01137","article-title":"Fluorofoldamer\u2010Based Salt\u2010 and Proton\u2010Rejecting Artificial Water Channels for Ultrafast Water Transport","volume":"22","author":"Shen J.","year":"2022","journal-title":"Nano Letters"},{"key":"e_1_2_7_56_1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1080\/10610278.2021.1999956","article-title":"Supramolecular Methods: The 8\u2010hydroxypyrene\u20101,3,6\u2010trisulfonic acid (HPTS) Transport Assay","volume":"33","author":"Gilchrist A. M.","year":"2021","journal-title":"Supramolecular Chemistry"},{"key":"e_1_2_7_57_1","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1039\/C0CS00062K","article-title":"Determining Association Constants From Titration Experiments in Supramolecular Chemistry","volume":"40","author":"Thordarson P.","year":"2011","journal-title":"Chemical Society Reviews"},{"key":"e_1_2_7_58_1","article-title":"Sequence\u2010Dependent Acylation of Peptide Lysine Residues by DNAzymes","volume":"25","author":"Das S. K.","year":"2024","journal-title":"Chembiochem"},{"key":"e_1_2_7_59_1","doi-asserted-by":"crossref","first-page":"12759","DOI":"10.1039\/D3CC02451B","article-title":"Stimuli\u2010Responsive Release of Active Anionophore From RGD\u2010Peptide\u2010Linked Proanionophore","volume":"59","author":"Srimayee S.","year":"2023","journal-title":"Chemical Communications"},{"key":"e_1_2_7_60_1","doi-asserted-by":"crossref","first-page":"21545","DOI":"10.1039\/D4NR03220A","article-title":"Stimuli\u2010Responsive Anion Transport Utilising Caged Hydrazone\u2010Based Anionophores","volume":"16","author":"Ahmad M.","year":"2024","journal-title":"Nanoscale"},{"key":"e_1_2_7_61_1","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1021\/jacs.2c12892","article-title":"Multistate Redox\u2010Switchable Ion Transport Using Chalcogen\u2010Bonding Anionophores","volume":"145","author":"Docker A.","year":"2023","journal-title":"Journal of the American Chemical Society"},{"key":"e_1_2_7_62_1","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202403667","article-title":"Redox\u2010Regulated Synthetic Channels: Enabling Reversible Ion Transport by Modulating the Ion\u2010Permeation Pathway","volume":"63","author":"Shi L.","year":"2024","journal-title":"Angewandte Chemie International Edition"}],"container-title":["Chemistry \u2013 A European Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.71794","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/chem.71794","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chem.71794","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:11:32Z","timestamp":1792044692000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.71794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,14]]},"references-count":61,"alternative-id":["10.1002\/chem.71794"],"URL":"https:\/\/doi.org\/10.1002\/chem.71794","archive":["Portico"],"relation":{},"ISSN":["0947-6539","1521-3765"],"issn-type":[{"value":"0947-6539","type":"print"},{"value":"1521-3765","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,14]]},"assertion":[{"value":"2026-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71794"}}