{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:39:16Z","timestamp":1792726756779,"version":"4.5.0"},"reference-count":52,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry A European J"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Oxidative phenol dearomatization using hypervalent iodine(III) reagents is a powerful tool for developing efficient synthetic routes to complex natural products and pharmaceuticals. This process enables the rapid formation of a functionalized dienone, a key intermediate derived from simple and inexpensive aromatic systems, thereby increasing structural complexity in a single step. Current methods, however, often require the use of perfluorinated alcohols as protic, non\u2010nucleophilic solvents, which environmentally harmful nature deteriorates the green metrics of the reaction. This paper presents a solvent\u2010free, mechanochemical methodology using a planetary ball mill to achieve the intramolecular oxidative dearomatization of several phenols that contain a heteronucleophile on a side chain. This process yields various spiranic systems within 5 min, with decent to good yields, and eliminates the need for expensive, environmentally harmful solvents. This approach has also been extended to a tandem Diels\u2013Alder process and the first application of a bimolecular example. This paper thus introduces a greener strategy for dearomatizing phenols using hypervalent iodines, offering a more sustainable path for this widely used synthetic transformation.<\/jats:p>","DOI":"10.1002\/chem.71836","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:12:27Z","timestamp":1792725147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypervalent Iodine Phenol Dearomatization Mediated by Mechanochemistry"],"prefix":"10.1002","author":[{"given":"J\u00e9r\u00e9mie","family":"Cuillerier","sequence":"first","affiliation":[{"name":"D\u00e9partement de Chimie Universit\u00e9 du Qu\u00e9bec \u00e0 Montr\u00e9al. 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