{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:46:36Z","timestamp":1762112796960},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2002,7,15]],"date-time":"2002-07-15T00:00:00Z","timestamp":1026691200000},"content-version":"vor","delay-in-days":195,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chirality"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Complexation of alkyl derivatives of 5\u2010ethyl\u20105\u2010phenyl\u20102\u2010thiobarbituric acid (2\u2010thiophenobarbital) enantiomers by \u03b2\u2010cyclodextrin was investigated by the AM1 method. The inclusion complexes of \u03b2\u2010cyclodextrin with neutral and anionic forms of these enantiomers have been modeled and energetically optimized. The chiral discrimination of enantiomers was analyzed in terms of differences in the interaction energies. The calculated interaction energies between each enantiomer of the investigated 2\u2010thiobarbiturates and \u03b2\u2010cyclodextrin confirm the ability of \u03b2\u2010cyclodextrin to act as a mobile phase additive in reversed\u2010phase HPLC to separate enantiomers by liquid chromatography and rationalize their order of elution. Chirality 14:632\u2013637, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/chir.10123","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T11:52:48Z","timestamp":1033905168000},"page":"632-637","source":"Crossref","is-referenced-by-count":15,"title":["Enantioselective chromatography of alkyl derivatives of 5\u2010ethyl\u20105\u2010phenyl\u20102\u2010thiobarbituric acid studied by semiempirical AM1 method"],"prefix":"10.1002","volume":"14","author":[{"given":"Krzysztof","family":"Zborowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grzegorz","family":"\u017buchowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,7,15]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"131","volume-title":"Chromatographic chiral separations","author":"Ward 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